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Single-cell RNA/TCR-seq of T cells from murine muscle injury and foreign body response to synthetic biomaterial implants

ABSTRACT: The main objective of this study is to characterize T cell response to tissue injury and foreign body response (synthetic polycaprolactone PCL implant). We isolate T cells from injured murine muscles with and without fibrotic PCL implants at various timepoints and perform transcriptomic profile using paired single-cell RNA/TCR-sequencing.

ORGANISM(S): Mus musculus

PROVIDER: GSE306147 | GEO | 2026/03/11

REPOSITORIES: GEO

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