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Gene expression of FACC canine cancer cell line panel (Affymetrix Canine 2.0 array)

ABSTRACT: Cancer cell line panels that incorporate genomic and pharmacologic screening data have become powerful tools for investigating the relationship between gene expression and drug response in human cancer research. Similar cell line panels of such a scale as the NCI60, CCLE, or GDSC do not currently exist in canine cancer research. Here we have assembled a canine cancer cell line panel of 29 cell lines representing multiple tumor types that have undergone gene expression profiling and have begun to be used for pharmacologic screening.

ORGANISM(S): Canis lupus familiaris

PROVIDER: GSE76126 | GEO | 2015/12/18

SECONDARY ACCESSION(S): PRJNA306370

REPOSITORIES: GEO

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Similar Datasets

Gene expression of FACC canine cancer cell line panel (Affymetrix Canine 2.0 array)

Project description:Cancer cell line panels that incorporate genomic and pharmacologic screening data have become powerful tools for investigating the relationship between gene expression and drug response in human cancer research. Similar cell line panels of such a scale as the NCI60, CCLE, or GDSC do not currently exist in canine cancer research. Here we have assembled a canine cancer cell line panel of 29 cell lines representing multiple tumor types that have undergone gene expression profiling and have begun to be used for pharmacologic screening. RNA was extracted from drug naÃ¯ve canine cancer cell lines and subjected to microarray analysis.

2015-12-18 | E-GEOD-76126 | biostudies-arrayexpress

Gene expression analysis in complex canine chronic cutaneous lupus erythematosus (CCLE)

Project description:We performed a comparative immunology case study of client-owned dogs to determine if immune and skin gene expression profiles in spontaneous canine chronic cutaneous lupus erythematosus (CCLE) with concomitant systemic autoimmunity mirror those observed in human CCLE.

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Expression data from the Cancer Cell Line Encyclopedia (CCLE)

Project description:The Cancer Cell Line Encyclopedia (CCLE) project is a collaboration between the Broad Institute, the Novartis Institutes for Biomedical Research and the Genomics Novartis Foundation to conduct a detailed genetic and pharmacologic characterization of a large panel of human cancer models It consists of a compilation of gene expression, chromosomal copy number, and massively parallel sequencing data from nearly 1,000 human cancer cell lines. All raw and processed data are available through an integrated portal on www.broadinstitute.org/ccle The final cell line collection spans 36 cancer types. Representation of cell lines for each cancer type was mainly driven by cancer mortality in the United States, as a surrogate of unmet medical need, as well as availability.

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SNP array data from the Cancer Cell Line Encyclopedia (CCLE)

2012-03-20 | E-GEOD-36138 | biostudies-arrayexpress

Expression data from the Cancer Cell Line Encyclopedia (CCLE)

2012-03-20 | GSE36133 | GEO

SNP array data from the Cancer Cell Line Encyclopedia (CCLE)

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Affymetrix 100K SNP array data-

Project description:allele call files from analysis of NCI60 cell line DNA on 100K SNP arrays. Keywords = NCI60, SNP array, cancer cell line Keywords: other

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miRNA expression of canine mammary cancer stem cells

Project description:The aim of our study was to assess miRNA expression of canine mammary cancer stem cells. Three canine mammary cancer cell lines (CMT-U27, CMT-U309 and P114) were stained using Anti-Sca1 (Stem cell antigen 1) antibodies. The FACS analysis showed 0,3-1% of Sca1+ cells in each of the cell line. The cells were sorted (using FACS Aria II) as Sca1+ and Sca1- and subjected to further analysis of miRNA expression (using Agilent custom miRNA microarray).

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Project description:Cancer Cell Line Encyclopedia (CCLE)

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SNP and Expression data from the Cancer Cell Line Encyclopedia (CCLE)

Project description:This SuperSeries is composed of the following subset Series: GSE36133: Expression data from the Cancer Cell Line Encyclopedia (CCLE) GSE36138: SNP array data from the Cancer Cell Line Encyclopedia (CCLE) Refer to individual Series

2012-03-20 | E-GEOD-36139 | biostudies-arrayexpress

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