The outer membrane protein of Riemerella anatipestifer YM strain interacting with duck vitronectin was screened by pull-down assay sequencing by mass spectrometry and search for complement escape related protein of Riemerella anatipestifer YM strain.

ABSTRACT: Riemerella anatipestifer can cause infectious serositis in ducklings with high mortality. Vitronectin acts as a complement regulator and plays a role in the terminal pathway of complement activation. It is a widely used strategy for Gram-negative bacteria to capture vitronectin to the surface of bacteria to inhibit complement activity. Therefore, we used duck vitronectin as bait protein, and screened the outer membrane protein of R. anatipestifer which can interact with duck vitronectin by pull-down assay, looking for the complement escape protein of R. anatipestifer, and laying a foundation for the prevention of R. anatipestifer.

ORGANISM(S): Riemerella Anatipestifer Ra-ym

SUBMITTER: Zutao Zhou  

PROVIDER: PXD039753 | iProX | Wed Feb 01 00:00:00 GMT 2023

REPOSITORIES: iProX