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Drying Enhances Signal Intensities for Global GC–MS Metabolomics

ABSTRACT: We report here that a straightforward change of the standard derivatization procedure for GC–MS metabolomics is leading to a strong increase in metabolite signal intensity. Drying samples between methoxymation and trimethylsilylation significantly increased signals by two- to tenfold in extracts of yeast cells, plant and animal tissue, and human urine. This easy step reduces the cost of sample material and the need for expensive new hardware.

INSTRUMENT(S): Gas Chromatography MS - Positive (GC-MS (Positive))

PROVIDER: MTBLS807 | MetaboLights | 2019-04-05

REPOSITORIES: MetaboLights

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			Action	DRS
	20151217_003.D.zip	Other
	20151217_004.D.zip	Other
	20151217_005.D.zip	Other
	20151217_007.D.zip	Other
	20151217_008.D.zip	Other

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