Metabolomics

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Liver and Plasma metaboites for 13C-glucose load in wild type, LIRKO GTT 1 mice


ABSTRACT: Mice were fasted for 18 hr overnight then sacrificed or treated with 13C-U-glucose (2 g/kg ip) and sacrificed 1 hr later by decapitation and liver was immediately freeze-clamped and stored in liquid N2 and then at -80 C. Wild type (IR and IR/FoxO1 floxed) mice were sacrificed after fasting and 1 hr post-glucose treatment. Liver-specific insulin receptor knockout (LIRKO) and insulin receptor/FoxO1 double knockout (LIRFKO) mice were sacrificed 1 hr post glucose treatment. http://www.nature.com/ncomms/2015/150512/ncomms8079/full/ncomms8079.html

ORGANISM(S): Mouse Mus Musculus

TISSUE(S): Liver

SUBMITTER: Maureen Kachman  

PROVIDER: ST000215 | MetabolomicsWorkbench | Fri Jun 12 00:00:00 BST 2015

REPOSITORIES: MetabolomicsWorkbench

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