Project description:This study describes the combined sequencing of the genomes and transcriptomes of single blastomeres from mouse 8-cell stage embryos.
Project description:Transcriptome analysis to map transcriptomes of Mps1DK p53null-driven aneuploid T-ALL, to determine correlation between copy number changes and expression changes and to map the transcriptional response to CIN Transcriptomes of T-ALL samples described in the accompanying manuscript were compared to the transcriptomes of thymocytes of 6-weeks old wild type mice
Project description:By analyzing thousands of vascular single cell transcriptomes from adult mouse brain, we provide molecular definitions of the principal vascular (endothelial and mural cells), and vascular-associated cell classes.
Project description:By analyzing about 1500 vascular single cell transcriptomes from adult mouse lung, we provide molecular definitions of the principal vascular (endothelial and mural cells), and vascular-associated cell classes.
Project description:Transcriptomes of mouse E12.5 primordial germ cells (PGCs), primordial germ cell-like cells (PGCLCs) isolated from 6-day culture embryoid bodies, and the precursor pluripotent stem cells [embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs)] and epiblast-like cells (EpiLCs) Total RNA was isolated from FACS-enriched, SSEA1+/CD61+ double-positive PGCs and PGCLCs. RNA was also isolated from ESC, iPSC, and EpiLC cultured without enrichment. Transcriptomes were determined using Affymetrix microarray.