Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Single Cell Analysis in trisomic tissues and organoids

ABSTRACT: Single Cell Analysis in trisomic tissues and organoids

PROVIDER: PRJEB49114 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Single Cell Analysis in trisomic tissues and organoids

Project description:Cortical organoids generated from mESC from a Down Syndrome (DS) mouse model (Ts65Dn) were dissociated for single cell sequencing to understand whether differential gene expression in DS brains affects cell diversity and how the molecular events that control the development of these diverse types of neocortical neurons are affected by the trisomy. These results were generated in parallel to a single cell experiment in forebrain fetal tissue from WT and Ts65Dn mice.

2023-03-15 | E-MTAB-12827 | biostudies-arrayexpress

Single cell analysis of osteosarcoma tissues

Project description:Single cell analysis of osteosarcoma tissues

| PRJNA638151 | ENA

Single-cell analysis of human kidney organoids

Project description:Single-cell analysis of human kidney organoids

| PRJNA476702 | ENA

Single-cell multi-omics profiling of brain organoids

Project description:Organoids were generated from H9 cells. Single cells were sorted from 4-month-old brain organoids differentiated using the telencephalon organoids protocol.

2023-07-10 | E-MTAB-13144 | biostudies-arrayexpress

RNA sequencing analysis of organoids and their parental tissues

Project description:RNA sequencing analysis of organoids and their parental tissues

| PRJNA679836 | ENA

Single-cell CRISPR screening of autism risk genes in brain organoids

Project description:Single-cell RNA sequencing of 4-month-old telencephalon organoids. Organoids were generated from cells infected with pooled lentivirus library. The lentiviral library delivers dual-gRNAs targeting 36 high-risk ASD genes in parallel. Organoids were dissociated after 4 months of in vitro differentiation and maturation. Single cells were sorted and subjected to 10X genomics 3' kits.

2023-07-09 | E-MTAB-13148 | biostudies-arrayexpress

RNA sequencing analysis of organoids and their parental tissues

Project description:We assessed whether organoids maintained the gene expression signatures of their parental healthy tissues and tumors. We performed transcriptomic analysis by bulk RNA sequencing (RNA-seq) across 3 mice, 3 patients and different periods iPSCs. Total RNA of organoids and their parental tissues were extracted at day 7 and day 0, respectively. Total RNA of iPSCs were extracted at day 0, day 1 and day 4. The results show that the organoids are able to replicate the inter-patient heterogeneity, which determines their feasibility on personalized therapy evaluation.

2020-11-21 | GSE161928 | GEO

Single-cell ATAC-seq of macaque cerebral organoids

Project description:Single cell ATAC-seq (scATAC-seq) was performed on macaque embryonic stem cell-derived cerebral organoids. scATAC-seq was performed on day 60 (2 months old cerebral organoid).

2019-10-16 | E-MTAB-8087 | biostudies-arrayexpress

Single cell RNA-Seq analysis of human skeletal muscle organoids

Project description:We performed single cell RNA sequencing analysis of human iPSC-derived skeletal muscle organoids at 12 week post differentiation stage.

2023-06-09 | GSE147512 | GEO

Single-cell ATAC-seq of bonobo cerebral organoids

Project description:Single cell ATAC-seq (scATAC-seq) was performed on bonobo induced pluripotent stem cells (iPSC) derived cerebral organoids. scATAC-seq was performed on day 60 (2 months old cerebral organoid) and day 120 (4 months old cerebral organoid).

2019-10-16 | E-MTAB-8083 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data