Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Nascent RNA profile in B, and T cells untreated and upon HU treatment

ABSTRACT: Nascent RNA profile in B, and T cells untreated and upon HU treatment

PROVIDER: PRJNA478134 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

EdU-seq profile in B,untreated and upon HU treatment

Project description:EdU-seq profile in B,untreated and upon HU treatment

| PRJNA478135 | ENA

END-seq profile in B,T, and HCT116 untreated and upon HU treatment

Project description:END-seq profile in B,T, and HCT116 untreated and upon HU treatment

| PRJNA478132 | ENA

Altered genes expression profile of Rep2 mutants in Fission Yeast upon HU treatment.

Project description:Expression profiles indicate that C-terminal of rep2 is essential for its transactivation activity. Keywords: rep2 mutants cells treated with 8 mM HU for different time points vs wildtype untreated cells

2010-01-08 | GSE10901 | GEO

Altered genes expression profile of Rep2 mutants in Fission Yeast upon HU treatment.

2010-05-16 | E-GEOD-10901 | biostudies-arrayexpress

HU treated cells vs wildtype untreated cells (asynchronized cells)

Project description:DNA replication checkpiont kinase rad3 (human ATM/ATR-like kinase) and cds1 (human CHK2-like kinase) are known to restore stalled replication forks and prevent subsequent cell cycle progression during a replication block imposed by HU-treatment in fission yeast. In order to identify cell cycle-specific exression which are modulated by replication checkpoint kinase rad3 and cds1, microarray approach was used to profile asynchronous and synchronous cells of wildtype and mutants treated and untreated with HU Keywords: HU treated cells vs wildtype untreated cells

2007-12-20 | GSE4280 | GEO

HU treatment of Sulfolobus solfataricus P2

Project description:Hydroxyurea (HU) is toxic to Sulfolobus cells. To address the basis of the HU toxicity, we performed transcriptome analyses on untreated cells and cells following exposure to 5 mM HU for 4 hours.

2016-10-05 | GSE87612 | GEO

HU treated cells vs wildtype untreated cells (elutriation centrifugation synchronized cells)

2007-12-20 | GSE4283 | GEO

Nascent RNA profile in B, and T cells untreated and upon HU treatment

Project description:In this study, we map sites of replication initiation and breakage in primary cells at high resolution under conditions of replication stress. We show that replication initiates between transcribed genes within nucleosome-depleted structures established by long asymmetrical poly(dA:dT) tracts flanking the initiation site. Paradoxically, large (>20 bp) homopolymeric (dA/dT) tracts are also preferential sites of polar replication fork stalling and collapse. We propose that the evolutionary expansion of poly(dA:dT) tracts in eukaryotic genomes serves to promote replication initiation, but at the cost of increasing chromosome fragility.

2018-08-01 | GSE116317 | GEO

ChIP-seq profile of RPA in B upon HU treatment

Project description:ChIP-seq profile of RPA in B upon HU treatment

| PRJNA478137 | ENA

EdU-seq profile in B,untreated and upon HU treatment

2018-08-01 | GSE116316 | GEO