Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap, instrument model
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Brain
SUBMITTER: Daniel Martins-de-Souza
PROVIDER: PXD000263 | Pride | 2013-10-09
REPOSITORIES: Pride
Iwata Keiko K Café-Mendes Cecilia C CC Schmitt Andrea A Steiner Johann J Manabe Takayuki T Matsuzaki Hideo H Falkai Peter P Turck Christoph W CW Martins-de-Souza Daniel D
Proteomics 20131120 23-24
Myelination of the CNS is performed by oligodendrocytes (OLs), which have been implicated in brain disorders, such as multiple sclerosis and schizophrenia. We have used the human oligodendroglial cell line MO3.13 to establish an OL reference proteome database. Proteins were prefractionationated by SDS-PAGE and after in-gel digestion subjected to nanoflow LC-MS analysis. Approximately 11 600 unique peptides were identified and, after stringent filtering, resulted in 2290 proteins representing nin ...[more]