Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Drosophila Melanogaster (fruit Fly)
SUBMITTER: Andreas Thomae
PROVIDER: PXD000489 | Pride | 2013-11-20
REPOSITORIES: Pride
Thomae Andreas W AW Schade Georg O M GO Padeken Jan J Borath Marc M Vetter Irene I Kremmer Elisabeth E Heun Patrick P Imhof Axel A
Developmental cell 20131114 4
Speciation involves the reproductive isolation of natural populations due to the sterility or lethality of their hybrids. However, the molecular basis of hybrid lethality and the evolutionary driving forces that provoke it remain largely elusive. The hybrid male rescue (Hmr) and the lethal hybrid rescue (Lhr) genes serve as a model to study speciation in Drosophilids because their interaction causes lethality in male hybrid offspring. Here, we show that HMR and LHR form a centromeric complex nec ...[more]