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Cellulophaga Bacteriophage - Multiple mechanisms drive phage infection efficiency in nearly identical hosts

ABSTRACT: Comparison of bacteria grown with phage that are specific or non-specific for the host

INSTRUMENT(S): LTQ Orbitrap Velos, Q Exactive

ORGANISM(S): Cellulophaga Baltica Nn016038

SUBMITTER: Matthew Monroe

LAB HEAD: Matthew Sullivan

PROVIDER: PXD005440 | Pride | 2018-10-22

REPOSITORIES: Pride

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Multiple mechanisms drive phage infection efficiency in nearly identical hosts.

Howard-Varona Cristina C Hargreaves Katherine R KR Solonenko Natalie E NE Markillie Lye Meng LM White Richard Allen RA Brewer Heather M HM Ansong Charles C Orr Galya G Adkins Joshua N JN Sullivan Matthew B MB

The ISME journal 20180322 6

Phage-host interactions are critical to ecology, evolution, and biotechnology. Central to those is infection efficiency, which remains poorly understood, particularly in nature. Here we apply genome-wide transcriptomics and proteomics to investigate infection efficiency in nature's own experiment: two nearly identical (genetically and physiologically) Bacteroidetes bacterial strains (host18 and host38) that are genetically intractable, but environmentally important, where phage infection efficie ...[more]

PMID: 29568113

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Multiple mechanisms drive phage infection efficiency in nearly identical hosts.

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Project description:Phosphoproteomic data from human MCF-7 cells treated with estrogen only or estrogen plus rapamycin, an mTOR inhibitor.

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Project description:Lipidomics, proteomics and metabolomics characterization of the ontogeny of lipid, protein and metabolite changes during normal postnatal lung development

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