Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Tooth Enamel
SUBMITTER: Federico Lugli
LAB HEAD: Giulia Di Rocco
PROVIDER: PXD012587 | Pride | 2019-11-05
REPOSITORIES: Pride
Lugli Federico F Di Rocco Giulia G Vazzana Antonino A Genovese Filippo F Pinetti Diego D Cilli Elisabetta E Carile Maria Cristina MC Silvestrini Sara S Gabanini Gaia G Arrighi Simona S Buti Laura L Bortolini Eugenio E Cipriani Anna A Figus Carla C Marciani Giulia G Oxilia Gregorio G Romandini Matteo M Sorrentino Rita R Sola Marco M Benazzi Stefano S
Scientific reports 20190911 1
Recent work has disclosed the critical role played by enamel peptides in sex classification of old skeletal remains. In particular, protein AMELY (amelogenin isoform Y) is present in the enamel dental tissue of male individuals only, while AMELX (isoform X) can be found in both sexes. AMELY can be easily detected by LC-MS/MS in the ion extracted chromatograms of the SM<sub>(ox)</sub>IRPPY peptide (monoisotopic [M + 2 H]<sup>+2</sup> mass = 440.2233 m/z). In this paper, we exploited the dimorphic ...[more]