Proteomics,Multiomics

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Sex Estimation Using Sexually Dimorphic Amelogenin Protein Fragments in Human Enamel


ABSTRACT: Sex estimation of human remains from demineralized blocks of tooth enamel by liquid chromatography tandem mass spectrometry (LC- MS/MS) and proteomic analysis of sexually dimorphic amelogenin peptides. The detection of the Y-isoform of amelogenin is used to estimate male sex. The combined signal intensity of the sexually dimorphic peptides from each samples of known sex is used to establish a statistical framework for the estimation of the female sex probability.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Tooth Enamel

SUBMITTER: Glendon Parker  

LAB HEAD: Glendon J Parker

PROVIDER: PXD009781 | Pride | 2018-11-29

REPOSITORIES: Pride

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