Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Optic Nerve
SUBMITTER: Sanjoy Bhattacharya
LAB HEAD: Sanjoy K. Bhattacharya, M. Tech., Ph. D.
PROVIDER: PXD016197 | Pride | 2020-05-26
REPOSITORIES: Pride
Chauhan Muhammad Zain MZ Arcuri Jennifer J Park Kevin K KK Zafar Maroof Khan MK Fatmi Rabeet R Hackam Abigail S AS Yin Yuqin Y Benowitz Larry L Goldberg Jeffrey L JL Samarah Mohammad M Bhattacharya Sanjoy K SK
iScience 20200114 2
Growth cones (GCs) are structures associated with growing neurons. GC membrane expansion, which necessitates protein-lipid interactions, is critical to axonal elongation in development and in adult neuritogenesis. We present a multi-omic analysis that integrates proteomics and lipidomics data for the identification of GC pathways, cell phenotypes, and lipid-protein interactions, with an analytic platform to facilitate the visualization of these data. We combine lipidomic data from GC and adult a ...[more]