Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture, Macrophage
DISEASE(S): Nephrolithiasis
SUBMITTER: Visith Thongboonkerd
LAB HEAD: Prof. Visith Thongboonkerd
PROVIDER: PXD027039 | Pride | 2021-11-03
REPOSITORIES: Pride
Communications biology 20210811 1
The association between kidney stone disease and renal fibrosis has been widely explored in recent years but its underlying mechanisms remain far from complete understanding. Using label-free quantitative proteomics (nanoLC-ESI-LTQ-Orbitrap MS/MS), this study identified 23 significantly altered secreted proteins from calcium oxalate monohydrate (COM)-exposed macrophages (COM-MP) compared with control macrophages (Ctrl-MP) secretome. Functional annotation and protein-protein interactions network ...[more]