Triatoma sordida salivary glands LC-MSMS

ABSTRACT: Triatoma sordida salivary glands secrete a number of complex bioactive proteins during feeding that affect hemostatic and immunological systems from vertebrate hosts. In this study, salivary glands and saliva were collected from 5th instar nymphs and adult triatomines. Liquid chromatography tandem-mass spectrometry (LC-MS/MS) was used to identify T. sordida salivary proteins. A total of 133 proteins was identified. Lipocalins, Hemiptera specific families, CRiSP/Antigen-5 and Kazal-type protein inhibitors proteins match to 42.01%, 14.32%, 5.86% and 1.91% of the total spectrum count, respectively. These proteins are involved in several physiological roles, including anti-coagulant, immunity and anti-microorganism. Salivary proteins contribute to successful feeding.

INSTRUMENT(S):

ORGANISM(S): Triatoma Sordida

TISSUE(S): Saliva

SUBMITTER: Carla Araújo  

LAB HEAD: Sèbastien Olivier Charneau

PROVIDER: PXD028350 | Pride | 2022-02-15

REPOSITORIES: Pride