Proteomics

Dataset Information

0

N-terminal proteome analysis on breast cell line

ABSTRACT: N-terminal peptide enrichment for ATE1 knockdown mutant breast cell line. Immortalized human breast cell line HMEC, and breast cancer cell line T47D were used.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Permanent Cell Line Cell, Cell Culture

DISEASE(S): Breast Cancer

SUBMITTER: Shinyeong Ju  

LAB HEAD: Cheolju Lee

PROVIDER: PXD035443 | Pride | 2025-09-15

REPOSITORIES: pride

Json Xml

Dataset's files

Source:
Action DRS
211203_Arg_breast_cancer_E01_bRP_F.msf Msf
211203_Arg_breast_cancer_E01_bRP_F.pdResult Other
211203_Arg_breast_cancer_E01_bRP_F01.raw Raw
211203_Arg_breast_cancer_E01_bRP_F02.raw Raw
211203_Arg_breast_cancer_E01_bRP_F03.raw Raw
Items per page:
1 - 5 of 51
altmetric image

Publications

ATE1 promotes breast cancer progression via arginylation-dependent regulation of MAPK-MYC signaling.

Nawale Laxman L   Ju Shinyeong S   Kim Jung Gi JG   Soung Nak Kyun NK   Kim Bo Yeon BY   Lee Cheolju C   Cha-Molstad Hyunjoo H  

Cell communication and signaling : CCS 20250902 1

<h4>Background</h4>Arginyl-tRNA-protein transferase (ATE1) catalyzes N-terminal arginylation, a regulatory protein modification implicated in various cellular processes, including proliferation, apoptosis, and migration. Although ATE1 has context-dependent roles in cancer, its specific function in breast cancer remains unclear. This study investigates the oncogenic role of ATE1 across multiple breast cancer subtypes and its underlying molecular mechanisms.<h4>Methods</h4>ATE1 expression in breas  ...[more]

Similar Datasets

Proteomics N-terminal and whole-protein profiling on R-catcher-enriched samples
2025-09-29 | PXD064220 | Pride
Genomics
| PRJNA1170264 | ENA
Transcriptomics T47D_MTVL treatment with JAK/STAT inhibitor AG490 with/without R5020
2007-10-12 | GSE9286 | GEO
Transcriptomics Next Generation Sequencing Facilitates Quantitative Analysis of human breast cancer cell T47D and T47D-TR Transcriptomes
2020-01-28 | GSE125738 | GEO
Genomics aCGH hybridization of breast cancer cell line T47D
2010-06-25 | GSE22547 | GEO
Transcriptomics Baseline Expression of Inflammatory Cytokines and Receptors in the T47D Human Breast Cancer Cell Line
2016-05-06 | GSE80647 | GEO
Genomics T47D Breast cancer cell line ChIP-seq data
| PRJNA415426 | ENA
Genomics Homo sapiens
| PRJNA128175 | ENA
Transcriptomics GLI1-regulated genes in human mammary epithelial cells and human breast cancer cells
2015-04-28 | GSE64350 | GEO
Transcriptomics Effects of HOTAIR RNAi on Transcriptomes in T47D Cells
2018-09-06 | GSE119511 | GEO