Protemic characterisation of the β-thalassemia erythroid cells from immortalised cell lines

ABSTRACT: β-thalassemia cell lines were generated via CRISPR-Cas9 genome editing of Bristol Erythroid Line Adult (BEL-A) and differentiated to the basophilic and polychromatic erythroid cell stage. TMT comparative proteomics was then performed on stage matched WT and β-thalassemia cells isolated by FACS.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Cell, Cell Culture

DISEASE(S): Beta Thalassemia

SUBMITTER: Debbie Daniels  

LAB HEAD: Jan Frayne

PROVIDER: PXD044730 | Pride | 2023-10-24

REPOSITORIES: Pride