Cross-Link of inactive PhK and GP

ABSTRACT: Phosphorylase kinase (PhK) phosphorylates GP to initiate glycogenolysis. To gain insights into the mechanism of PhK catalyzing GP phosphorylation, we have tried a variety of methods to obtain the hPhK-GP complex, but none of them were successful. Eventually, we decided to employ XL-MS to investigate the interaction between PhK and GP.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Suspension Culture

SUBMITTER: Ruifang Ma  

LAB HEAD: Kaige Yan

PROVIDER: PXD059356 | Pride | 2025-05-07

REPOSITORIES: Pride