Dataset Information

Temporally graded K48 polyubiquitin targets in the male amygdala following contextual fear conditioning

ABSTRACT: Temporally graded K48 polyubiquitin targets in the male amygdala following contextual fear conditioning

INSTRUMENT(S):

ORGANISM(S): Rattus Norvegicus (rat)

TISSUE(S): Brain, Amygdala

DISEASE(S): Post-traumatic Stress Disorder

SUBMITTER: Keith Ray

LAB HEAD: Timothy J. Jarome

PROVIDER: PXD070314 | Pride | 2026-04-27

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	250812_TJ_B01_01_RA5_1_2211.d.zip	Other
	250812_TJ_B01_01_RA5_1_2211.mgf	Mgf
	250812_TJ_B01_02_RA5_1_2212.d.zip	Other
	250812_TJ_B02_01_YD3_1_2223.d.zip	Other
	250812_TJ_B02_02_YD3_1_2224.d.zip	Other

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Publications

Temporal- and sex-specific changes in proteasome-dependent and independent polyubiquitination in the amygdala during fear memory formation.

Brown Brieann B Preveza Natalie N Jones Gaurav G Turner Meagan M Ray W Keith WK Jarome Timothy J TJ

Learning & memory (Cold Spring Harbor, N.Y.) 20260331 4

Strong evidence has emerged over the last two decades implicating proteasome-dependent and independent protein polyubiquitination in the memory consolidation process. Recently, it was shown that multiple forms of polyubiquitination, including proteasome-dependent K48 and proteasome-independent M1 polyubiquitination, regulate fear memory formation in a sex-dependent manner in the amygdala. However, prior work focused on single time points during the postlearning period, leaving questions about wh ...[more]

PMID: 41916668

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