Mouse serum DIA-based proteomic profiling after 1-day or 7-day daily heat stress exposure

ABSTRACT: This project profiles heat stress (HS)-induced alterations in the mouse serum proteome to identify circulating proteins that are consistently regulated by HS. Mice were assigned to three groups: PF (pair-fed control at room temperature, RT), HS1D (daily HS for 1 day, 6 h/day), and HS7D (daily HS for 7 consecutive days, 6 h/day). The PF group serves as the shared control and was collected at the same time point as the HS1D group (RT, 1 day), providing a reference for HS-associated changes. The primary objective is to identify overlapping proteomic changes in both HS groups relative to PF, highlighting robust HS-responsive circulating proteins.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Blood Serum

SUBMITTER: Xu Feng  

LAB HEAD: Xiang-Hang Luo

PROVIDER: PXD074893 | Pride | 2026-04-28

REPOSITORIES: Pride