Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Bulk RNAseq of hippocampus at PDN3

PROVIDER: PRJNA1070264 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR27748432_1.fastq.gz	Fastqsanger.gz
	SRR27748432_2.fastq.gz	Fastqsanger.gz
	SRR27748433_1.fastq.gz	Fastqsanger.gz
	SRR27748433_2.fastq.gz	Fastqsanger.gz
	SRR27748434_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Project description:Bulk RNAseq of Cerebelum at PDN3

| PRJNA1070547 | ENA

Project description:Bulk RNAseq of cortex prefrontal at PDN3

| PRJNA1070311 | ENA

Project description:Bulk RNAseq of dural meninges at PDN3

| PRJNA1069236 | ENA

Effect of short-term high fat diet consumption on hippocampal and amygdalar gene expression in adult and aged male rats

Project description:It is known that short-term high fat diet consumption leads to significant memory impairments and an exaggerated proinflammatory phenotype in the aged rat brain. To gain a better understanding of the underlying mechanisms driving this cognitive and proinflammatory response, we conducted bulk RNAseq analysis of the hippocampus and amygdala from young adult and aged male rats.

2023-02-15 | GSE223802 | GEO

Project description:Hippocampus erectus brain RNAseq

| PRJNA753805 | ENA

Characterization of the transcriptional landscape of human developing hippocampus by ATAC-seq

Project description:Human hippocampus enabled further processing of higher brain functions. However, very little is known about human hippocampus development, which is largely accomplished during fetal stage. Our current study elucidates the transcriptomic profiling of the developing human fetal hippocampus using single-cell RNA-seq (scRNA-seq) and bulk atac-seq, allowing us to reconstruct the order of neurogenesis and their lineage relationships.

2019-11-13 | GSE131256 | GEO

Multi-angled transcriptome analyses reveal chameleon-like behavior of macrophages in the porcine respiratory tract

Project description:Macrophages have a pivotal role during viral infections in pigs. By expressing cell surface receptors, macrophages become viral targets and reservoirs. In the case of upper respiratory tract infections, many viruses target the peripheral nasal mucosa. Recent in vivo and in vitro (primary nasal cell cultures) porcine reproductive and respiratory syndrome virus (PRRSV) studies demonstrated that several macrophage subsets exist in the porcine nasal mucosa, and that virus strains with different virulence showed altered tropism for these different macrophage populations. To further investigate these macrophage subsets, total RNA sequencing was performed in parallel on two subsets from the nasal mucosa and lung macrophages. Macrophages were isolated by either fluorescent activated cell sorting (FACS; cf. bulk RNAseq) or laser capture microdissection (LCM; cf. LCM RNAseq) in combination with immunofluorescence staining against two macrophage markers, CD163 and Sialoadhesin (Sn). With both RNAseq methods, nasal macrophages showed a different transcriptomic profile compared to lung macrophages. Differentially expressed genes were identified in the two subsets of nasal macrophages. Gene set enrichment analysis on the three macrophage populations showed that GO terms and KEGG pathways on LCM RNAseq data were more specific to the spatial location of macrophage subsets than bulk RNAseq data. Cell type signature analysis revealed that nasal CD163+Sn- cells resemble squamous epithelial cells (LCM RNAseq) or antigen presenting cells (bulk RNAseq) while nasal CD163+Sn+ cells are more like fibroblasts/stromal cells (LCM RNAseq) or vascular endothelial cell (bulk RNAseq). Our results confirmed that not only macrophages in different tissues but also macrophages in different areas within the same tissue have different transcriptional programs, suggesting their differential roles in their interaction with pathogens and corresponding immune responses.

2023-09-29 | E-MTAB-12120 | biostudies-arrayexpress

Mutations in RAS pathway induce synthetic lethality of MEK inhibition with mitochondrial oxidative metabolism in acute myeloid leukemia

Project description:Bulk RNAseq of primary AML samples at diagnosis

2021-12-31 | E-MTAB-10048 | biostudies-arrayexpress

Single cell-derived spheroids capture the self-renewing subpopulations of metastatic ovarian cancer, BulkRNA-seq

Project description:bulk RNAseq data from human patients and generated colture at different condition

2023-07-21 | E-MTAB-11194 | biostudies-arrayexpress

Bulk RNAseq for B1a B cells of WT and IRF4 T95R mutant mice

Project description:Bulk RNAseq of splenic B1a B cells from wild-type and IRF4 T95R heterozygous mice.

2023-06-01 | E-MTAB-11262 | biostudies-arrayexpress