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Impact of Chronic Olanzapine Administration on Gene Expression in the Mouse Lateral Septum

ABSTRACT: Impact of Chronic Olanzapine Administration on Gene Expression in the Mouse Lateral Septum

PROVIDER: PRJNA1119214 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR29258660_1.fastq.gz	Fastqsanger.gz
	SRR29258660_2.fastq.gz	Fastqsanger.gz
	SRR29258661_1.fastq.gz	Fastqsanger.gz
	SRR29258661_2.fastq.gz	Fastqsanger.gz
	SRR29258662_1.fastq.gz	Fastqsanger.gz

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Impact of Chronic Olanzapine Administration on Gene Expression in the Mouse Lateral Septum

Project description:To explore the effects of long-term olanzapine treatment on gene expression in the lateral septum of female mice, we conducted a study using female C57BL/6 mice fed with olanzapine-supplemented chow for 12 weeks. The treated mice exhibited significant weight gain and lipid alterations compared to the control group. Subsequently, RNA-seq was performed on the lateral septum brain regions of both the treated and control mice, followed by gene expression profiling to analyze the data.

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The lateral septum orchestrates state-dependent modulation of associative threat memory dynamics across the ovarian hormone cycle

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