Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Cryptococcus neoformans strain:CN_2024

ABSTRACT: Cryptococcus neoformans strain:CN_2024 Genome sequencing

PROVIDER: PRJNA1119728 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Ribosome profiling of Cryptococcus neoformans H99

Project description:We measured protein translation (by ribosome profiling) and RNA levels (by polyA-enriched RNA-seq) in Cryptococcus neoformans strain H99 and Cryptococcus neoformans strain JEC21. This is the first transcriptome-wide map of translation in this species complex.

2019-06-22 | GSE133125 | GEO

Cryptococcus neoformans strain TJ1854 derived amphotericin B adaptors

Project description:In this study, H99 is a wild type Cryptococcus neoformans strain. TJ1854 is a chromosome 4 disomy strain derived from H99. Approximately 1 million cells of TJ1854 were spread on YPD plate supplemented with 6ug/ml amphtericin B. Randomlyh 27 adaptors (TJ2487-TJ2513) were chosen. These adaptors were sequenced.

2023-03-15 | E-MTAB-12480 | biostudies-arrayexpress

Transcriptome analysis of one aneuploid Cryptococcus neoformans strain

Project description:Cryptococcus neoformans lab strain H99 was used to obtain tunicamycin adaptors. Transcriptome of one aneuploid adaptor, FY1381, was compared to parent.

2022-10-22 | E-MTAB-12275 | biostudies-arrayexpress

iCNG99: a validated genome-scale metabolic model of Cryptococcus neoformans strain H99

Project description:Cryptococcus neoformans is a ubiquitous environmental fungus that can also cause life-threatening infections in immunocompromised individuals. As a competent pathogen, Cryptococcus needs to reprogram its metabolism to adapt the drastic differences between environmental niches and host niches. A well-curated genome-scale metabolic model (GEM) is a powerful tool to facilitate the investigation of the metabolic resilience of an organism Here we reconstructed and validated iCNG99, a GEM for C. neoformans reference strain H99, and evaluated its predictive performance across 43 growth conditions and gene essentiality benchmarks. The model achieved high confidence essential gene prediction (precision = 0.77) and recapitulated pathways targeted by clinically available antifungals. Integration with transcriptomic and metabolomic data enabled iCNG99 to capture condition-specific metabolic adaptations and to identify candidate vulnerabilities in drug tolerance, revealing metabolic adaptations associated with survival within host conditions and drug susceptibility. Together, iCNG99 provides a systems-level computational platform for investigating C. neoformans metabolism and for prioritizing antifungal vulnerabilities.

2026-04-13 | GSE327336 | GEO

Whole genome sequecing of Cryptococcus neoformans treated with tunicamycin adaptors

Project description:We exposed Cryptococcus neoformans lab strain H99 to tunicamycin and obtained some adaptors. We did whole genome sequencing of these adaptors as well as the parent.

2021-04-29 | E-MTAB-10356 | biostudies-arrayexpress

Whole genome sequencing of fluconazole adaptors in Cryptococcus neoformans

Project description:Cryptococcus neoformans lab strain H99 was exposed to fluconazole. Adaptors which obtained tolerance to fluconazole were sequenced

2021-03-13 | E-MTAB-10177 | biostudies-arrayexpress

Whole genome sequencing of benomyl adaptors in Cryptococcus neoformans

Project description:Cryptococcus neoformans lab strain H99 was spread on YPD plate supplemented with 4ug/ml benomyl. Randomly 60 adaptors were sequenced.

2023-07-11 | E-MTAB-12410 | biostudies-arrayexpress

Whole genome sequencing of chlorothalonil adaptors in Cryptococcus neoformans

Project description:Cryptococcus neoformans lab strain H99 was spread on YPD plate supplemented with 2.5ug/ml chlorothalonil. Randomly 72 adaptors were sequenced.

2023-05-03 | E-MTAB-12416 | biostudies-arrayexpress

Whole genome sequencing of azoxystrobin adaptors in Cryptococcus neoformans

Project description:Cryptococcus neoformans lab strain H99 was spread on YPD plate supplemented with 16 ug/ml azoxystrobin. Randomly 60 adaptors were sequenced.

2023-07-14 | E-MTAB-12417 | biostudies-arrayexpress

Whole genome sequencing of pyraclostrobin adaptors in Cryptococcus neoformans

Project description:Cryptococcus neoformans lab strain H99 was spread on YPD plate supplemented with 1.5ug/ml pyraclostrobin. Randomly 23 adaptors were chosen. These adaptors were sequenced.

2023-04-06 | E-MTAB-12415 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data