Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

MiRNA microarray expression from glioblastoma & astrocytes under 100V/m 48hr dcEF stimulation & sham

ABSTRACT: miRNA microarray expression from glioblastoma & astrocytes under 100V/m 48hr dcEF stimulation & sham

PROVIDER: PRJNA1132972 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

miRNA microarray expression from glioblastoma & astrocytes under 100V/m 48hr dcEF stimulation & sham

Project description:Direct current electric field mimicking a physiological electrical field from transepithelial potential difference can direct cell migration (electrotaxis)and cellular signaling. While the transcriptome in dcEF has been reported and more studied, the miRNA expression of cells under dcEF stimulation is less understood. We use a reversibly sealed dcEF stimulation bioreactor to apply uniform dcEF to glioblastoma cell lines and primary astrocytes and investigate if dcEF can induce differential expression of cellular miRNA and exosomal miRNA expression that can regulate the gene expression

2025-07-11 | GSE271714 | GEO

Microarray of Sirt1 KO and control astrocytes after cocktail stimulation

Project description:Microarray of Sirt1 KO and control astrocytes after cocktail stimulation

| PRJNA878473 | ENA

Tumor-associated Reactive Astrocytes Aid the Evolution of Immunosuppressive Environment in Glioblastoma

Project description:The role of activated astrocytes in glioblastoma environment

2019-03-20 | GSE128536 | GEO

Exosome-transmitted RVT1 from reactive astrocytes promotes recurrence glioblastoma proliferation

Project description:Glioblastoma (GBM) remains among the most lethal brain tumors despite improvements in treatment. Surgical resection is a universal component of glioma therapy. However, the mechanism underlying postoperative recurrence remains a challenge due to limited information regarding the changes that occur in the postoperative microenvironment. Here, we show that a subtype of proinflammatory reactive astrocytes designated is induced by inflammatory cytokines or injury. We show that reactive astrocytes can secrete the long noncoding RNA (lncRNA) LOC646762 to promotes recurrence glioblastoma proliferation in an exosome-dependent manner.We firstly named this reactive astrocyte associated lnRNA as “lnc-RVT1”.

2018-06-08 | GSE115459 | GEO

Expression data from glioblastoma stem-like cells and their differentiated progeny co-cultured with astrocytes

Project description:Glioblastoma stem-like cells or their differentiated progeny were co-cultured for 48h with normal human astrocytes to detect if invasion associated genes were influenced Co-cultured samples and controls, a total 24 samples were selected for RNA extraction and hybridization on Affymetrix microarrays.

2012-04-08 | E-GEOD-37120 | biostudies-arrayexpress

Crosstalk with astrocytes establishes tumor edge in glioblastoma

Project description:Crosstalk with astrocytes establishes tumor edge in glioblastoma

| PRJNA558772 | ENA

Microarray of Sirt1 KO and control astrocytes after cocktail stimulation

Project description:The affection of Sirt1 on astrocyte is not well understanded. Here we studied the change of RNA expression profile after Sirt1 knockout in primary astrocyte after stimulating with A1 astrocyte inducing cocktails. To analyze the change of RNA expression profile after Sirt1 knockout in astrocytes, we built Sirt1 knockout and control astrocytes using crispr technique, and analyzed RNA expression profiles of Sirt1 KO and control astrocytes after treating with cocktail (C1q, IL-1α, TNF-α) by using microarray.

2022-10-17 | GSE212924 | GEO

Sham vs.BCAS microarray for brain

Project description:Sham vs.BCAS microarray for brain

| PRJNA908806 | ENA

Expression data from glioblastoma stem-like cells and their differentiated progeny co-cultured with astrocytes

Project description:Glioblastoma stem-like cells or their differentiated progeny were co-cultured for 48h with normal human astrocytes to detect if invasion associated genes were influenced

2012-04-09 | GSE37120 | GEO

Comparative proteomic analysis of EV-derived from glioblastoma (LN 229 cell line) and healthy human astrocytes, neurons and endothelial brain cells

Project description:This study aims to identify EV-derived glioblastoma biomarkers through a comparative mass spectrometry-based bottom-up proteomic analysis of glioblastoma LN-229 cell line and healthy human neurons, astrocytes, and endothelial brain cells (HEBC). The work investigates cancer cells' communication with the healthy brain environment

2024-09-03 | PXD055487 |

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data