Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Microarray of Sirt1 KO and control astrocytes after cocktail stimulation

ABSTRACT: Microarray of Sirt1 KO and control astrocytes after cocktail stimulation

PROVIDER: PRJNA878473 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Microarray of Sirt1 KO and control astrocytes after cocktail stimulation

Project description:The affection of Sirt1 on astrocyte is not well understanded. Here we studied the change of RNA expression profile after Sirt1 knockout in primary astrocyte after stimulating with A1 astrocyte inducing cocktails. To analyze the change of RNA expression profile after Sirt1 knockout in astrocytes, we built Sirt1 knockout and control astrocytes using crispr technique, and analyzed RNA expression profiles of Sirt1 KO and control astrocytes after treating with cocktail (C1q, IL-1α, TNF-α) by using microarray.

2022-10-17 | GSE212924 | GEO

Differential expression in colon epithelial organoids post proinflammatory cocktail stimulation

Project description:RNA-seq analysis (proinflammatory cocktail vs. control) of total RNA isolated from patient-derived colon organoids established from an ulcerative colitis patient. The analysis aimed at characterizing the epithelial gene expression changes post proinflammatory stimulation. ***Please note that raw data is not provided as Norwegian law does not allow public access to human sequences raw data

2026-05-26 | GSE289072 | GEO

miRNA microarray expression from glioblastoma & astrocytes under 100V/m 48hr dcEF stimulation & sham

Project description:Direct current electric field mimicking a physiological electrical field from transepithelial potential difference can direct cell migration (electrotaxis)and cellular signaling. While the transcriptome in dcEF has been reported and more studied, the miRNA expression of cells under dcEF stimulation is less understood. We use a reversibly sealed dcEF stimulation bioreactor to apply uniform dcEF to glioblastoma cell lines and primary astrocytes and investigate if dcEF can induce differential expression of cellular miRNA and exosomal miRNA expression that can regulate the gene expression

2025-07-11 | GSE271714 | GEO

Effect of IL-1α/TNFα/C1q Cocktail on gene expression of astrocytes

Project description:Effect of IL-1α/TNFα/C1q Cocktail on gene expression of astrocytes

| PRJNA891234 | ENA

miRNA microarray expression from glioblastoma & astrocytes under 100V/m 48hr dcEF stimulation & sham

Project description:miRNA microarray expression from glioblastoma & astrocytes under 100V/m 48hr dcEF stimulation & sham

| PRJNA1132972 | ENA

Involvement of SIRT1-regulated transcription profiles in prostate cancer

Project description:In order to understand the mechanism associated with SIRT1-mediated development of prostate cancer progression, we conducted RNA-sequencing analysis in SIRT1 suppressed hormone sensitive prostate cancer cells (LNCaP) under conditions of androgen sufficiency, deprivation, androgen stimulation or AR suppression.

2021-05-22 | GSE152820 | GEO

In vivo chemical reprogramming of astrocytes into neurons

Project description:We established a chemical cocktail that converts astrocytes into neuronal-like cells in vitro.

2021-01-08 | GSE164421 | GEO

Effect of IL-1α/TNFα/C1q Cocktail on gene expression of astrocytes

Project description:To investigate the gene expression difference between resting astrocytes and C3d+ reactive astrocytes.

2022-10-22 | GSE215888 | GEO

RNAseq in Sirt1 wild-type or conditional KO mouse T-ALLs

Project description:C57BL6 mice harboring Sirt1 conditional knockout NOTCH1-DE-induced leukemias were treated with vehicle (control) or tamoxifen to induce isogenic deletion of Sirt1. Here we report the gene expression profile of leukemic blasts obtained from the spleen from control- or tamoxifen-treated leukemic mice.

2022-12-08 | GSE203387 | GEO

Microarray analysis of liver-specific Sirt1 knockout mice lung tissue

Project description:To explore the pathology of liver-specific Sirt1 knockout mice. To specify, the liver-specific Sirt1 knockout mice commenced high blood glucose within three months. When the mice age extended to one year, the mice present surprising higher lung tumor vulnerabilities in contrast to wild type, we explore the underlying mechanism of the symptom

2026-04-04 | GSE326924 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data