Homo sapiens
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ABSTRACT:
PROVIDER: PRJNA255333 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Peripheral blood mononuclear cells, control vs. Kashin-Beck Disease
| PRJNA147433 | ENA
Project description:Objective: To investigate the differences between the gene expression profiles in peripheral blood mononuclear cells (PBMC) from normal controls and patients with Kashin-Beck disease (KBD). Methods: Twenty KBD patients and 12 normal subjects were selected from a KBD-endemic area and divided into four pairs of KBD vs. control (KBD, n=5 per pair; control, n=3 per pair). RNAs were respectively isolated from KBD PBMCs and normal PBMCs. Gene expression profiles were analyzed by oligonucleotide microarray.
2011-09-23 | GSE32127 | GEO
Project description:Objective: To investigate the differences between the gene expression profiles in peripheral blood mononuclear cells (PBMC) from normal controls and patients with Kashin-Beck disease (KBD). Methods: Twenty KBD patients and 12 normal subjects were selected from a KBD-endemic area and divided into four pairs of KBD vs. control (KBD, n=5 per pair; control, n=3 per pair). RNAs were respectively isolated from KBD PBMCs and normal PBMCs. Gene expression profiles were analyzed by oligonucleotide microarray. Two-condition experiment, control vs. KBD PBM cells. Biological replicates: 4 control replicates, 4 KBD replicates.
2011-09-22 | E-GEOD-32127 | biostudies-arrayexpress
Project description:Kashin-Beck disease (KBD) is an endemic and chronic osteochondropathy with unknown etiology. The disease mostly occurs in children between the ages of 3 and 13 in a diagonal belt-like area ranging from Northeast to Southwest China. We carried out this microarray analysis to investigate the differences in gene expression levels between KBD patients and healthy controls. Total RNA was isolated from peripheral blood mononuclear cells (PBMCs).
2014-08-30 | E-MTAB-2494 | biostudies-arrayexpress
Project description:Objective:To identify an accurate blood-based gene signature for early detection of Kashin-Beck disease (KBD). Methods: Gene expression analysis was conducted of peripheral blood samples from 100 patients with KBD and 100 controls randomly chosen from two KBD-endemic areas Two-condition experiment, Control vs. KBD PBM cells. Biological replicates: 100 control replicates, 100 KBD replicates.
2014-07-16 | E-GEOD-59446 | biostudies-arrayexpress
Project description:Transcription profiling by array of human peripheral blood mononuclear cells from patients with peripheral arterial disease
2025-01-24 | E-GEOD-27034 | ExpressionAtlas
Project description:Objective:To identify an accurate blood-based gene signature for early detection of Kashin-Beck disease (KBD). Methods: Gene expression analysis was conducted of peripheral blood samples from 100 patients with KBD and 100 controls randomly chosen from two KBD-endemic areas
2014-07-16 | GSE59446 | GEO
Project description:Transcription profiling of human peripheral blood mononuclear cells treated with a CDK inhibitor
2025-01-24 | E-GEOD-15389 | ExpressionAtlas
Project description:Genome-Scale draft model for Human Peripheral Blood Mononuclear Cells (PBMCs). A GEM for PBMCs was developed by applying the INIT
algorithm on Human Metabolic Reconstruction (HMR 2.0) as a template model. GEMs were contextualised/ constrained for different conditions using expression datasets. The gene/transcript expression data obtained from PBMCs of Type 1 Diabetes progressors, non-progressors, and healthy controls were employed to score each reaction of HMR 2.0. For further detail please refer to Electronic Supplementary Information of Sen et.al, Metabolic alterations in immune cells associate with progression to type 1 diabetes, Diabetologia, 15/01/2020, (https://doi.org/10.1007/s00125-020-05107-6).
2020-03-11 | MODEL1905270001 | BioModels
Project description:RNA-seq of coding RNA in human fibroblasts, Peripheral Blood Mononuclear Cells (PBMCs) and induced pluripotent stem cells (iPS cells) as part of the HipSci project
2025-01-23 | E-MTAB-4748 | ExpressionAtlas