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Genome-wide maps of c-Myc binding sites in myoblasts and myotubes

ABSTRACT: Genome-wide maps of c-Myc binding sites in myoblasts and myotubes

PROVIDER: PRJNA430194 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR6495770_1.fastq.gz	Fastqsanger.gz
	SRR6495770_2.fastq.gz	Fastqsanger.gz
	SRR6495767_1.fastq.gz	Fastqsanger.gz
	SRR6495767_2.fastq.gz	Fastqsanger.gz
	SRR6495768_1.fastq.gz	Fastqsanger.gz

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Genome-wide maps of c-Myc binding sites in myoblasts and myotubes

Project description:By applying ChIP-seq, we generated genome-wide maps of c-Myc in skeletal myoblasts and myotubes. We found that c-Myc binds to 19354 confident target with a large portion residing in the intergenic regions. In addition, c-Myc was found to regulate many loci. Further detailed study revealed that c-Myc can regulate some genes, miRNAs, and lincRNAs which are fucntional in skeletal myogenesis. In this study, we identified a c-Myc induced regulatory pathway in myogensis.

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