Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Blood-feeding strategy of Hirudo nipponia salivary gland

PROVIDER: PRJNA477463 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR7411510.fastq.gz	Fastqsanger.gz
	SRR7411511.fastq.gz	Fastqsanger.gz
	SRR7411512.fastq.gz	Fastqsanger.gz
	SRR7411513.fastq.gz	Fastqsanger.gz
	SRR7411514.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 9

Similar Datasets

Proteomic study of salivary gland starvation stress in Hirudo nipponia based on non-labeling quantitative method

Project description:Hirudo nipponia is an important traditional Chinese medicine resource in China, and the secretions of its salivary glands contain a variety of protein bioactive substances, but due to the low concentration and abundance, they have not been more characterized, and the exploration of its salivary glands is of great significance for the study of the medicinal value and secretion mechanism of leeches. Methods: The expression of differential proteins in salivary gland tissues under starvation (D30) and feeding (D0) states was compared by label-free protein quantification and bioinformatics analysis.

2024-07-03 | PXD045479 | Pride

Transcriptomic and functional analysis of the Anopheles gambiae salivary gland in relation to blood feeding

Project description:Background: The Anopheles gambiae salivary glands play a major role in malaria transmission and express a variety of bioactive components that facilitate blood-feeding by preventing platelet aggregation, blood clotting, vasodilatation, and inflammatory and other reactions at the probing site on the vertebrate host. Results: We have performed a global transcriptome analysis of the A. gambiae salivary gland response to blood-feeding, to identify candidate genes that are involved in hematophagy. A total of 4,978 genes were found to be transcribed in this tissue. A comparison of salivary gland transcriptomes prior to and after blood-feeding identified 52 and 41 transcripts that were significantly up-regulated and down-regulated, respectively. Ten genes were further selected to assess their role in the blood-feeding process using RNAi-mediated gene silencing methodology. Depletion of the salivary gland genes encoding D7L2, anophelin, peroxidase, the SG2 precursor, and a 5'nucleotidase gene significantly increased probing time of A. gambiae mosquitoes and thereby their capacity to blood-feed. Conclusions: The salivary gland transcriptome comprises approximately 38% of the total mosquito transcriptome and a small proportion of it is dynamically changing already at two hours in response to blood feeding. A better understanding of the salivary gland transcriptome and its function can contribute to the development of pathogen transmission control strategies and the identification of medically relevant bioactive compounds.

2011-11-01 | GSE33385 | GEO

Transcriptomic and functional analysis of the Anopheles gambiae salivary gland in relation to blood feeding

2011-11-01 | E-GEOD-33385 | biostudies-arrayexpress

Project description:RNA-Seq of salivary glands: Hirudo nipponia

| PRJNA1086883 | ENA

Differential expression of Aedes aegypti salivary gland transcriptome upon blood feeding

2009-12-31 | GSE16392 | GEO

Hirudo nipponia

Project description:Hirudo nipponia Metagenome

| PRJNA421854 | ENA

Hirudo nipponia

Project description:Hirudo nipponia overview

| PRJNA422000 | ENA

Using proteomics data to reveal the role of aaNAT1 in the salivary glands of Aedes aegypti and the changes in salivary gland proteins after blood feeding

Project description:Collect the salivary glands of Aedes aegypti that were injected with AaaaNAT1 dsRNA, injected with GUS dsRNA, subjected to blood feeding, and untreated, respectively. Perform proteomic analysis on these four samples to reveal the role of aaNAT1 in the salivary glands of Aedes aegypti and the changes in salivary gland proteins after blood feeding, using the proteomics data.

2025-11-15 | PXD070806 |

Differential expression of Aedes aegypti salivary gland transcriptome upon blood feeding

Project description:We have developed an oligoGEArray with 434 genes from Ae. aegypti salivary gland. OligoGEArray was customized with the salivary gland genes chosen from the transcriptome source published by Ribeiro et al (2007). Oligonucleotides (60bp) were designed and array were manufactured by SABiosciences. Using this OligoGEArray, we analyzed the differential expression of salivary trancritptome upon blood feeding. Salivary glands were dissected from 1, 3, 24 and 48 hours post fed (hpf) and unfed Ae. aegypti. Total RNA were extracted and the differential expression of transcriptome were analysed. Quantitative Real-Time PCR was performed on selected genes to validate the OligoGEArray data.

2010-06-24 | E-GEOD-16392 | biostudies-arrayexpress

Ornithodoros Lahorensis Salivary gland LC-MSMS

Project description:Ticks are hematophagous vectors of great medical and veterinary importance because they transmit numerous pathogenic microorganisms to humans and animals. The argasid Ornithodoros lahorensis is the vector of tickborne Anaplasma ovis,Crimean-Congo haemorrhagic fever virus and other pathogenic. Tick salivary gland express bioactive molecules that perform key functions in blood feeding and pathogen transmission. To explore new strategies for tick control, in this work we have obtained and compared the salivary gland proteomics of O.lahorensis before and after a blood meal and identified the DEPs regulated after feeding. The proteins were annotated, functionally and their expression levels compared between both physiological conditions (unfed females/males and fed females/males at 24h post-engorgement).

2025-12-08 | PXD059319 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data