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Transgenic expression of human C19MC miRNAs impacts placental morphogenesis

ABSTRACT: Transgenic expression of human C19MC miRNAs impacts placental morphogenesis

PROVIDER: PRJNA592184 | ENA |

REPOSITORIES: ENA

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Transgenic expression of human C19MC miRNAs impacts placental morphogenesis

Project description:Transgenic mice carrying the human C19MC locus expressing a family of primate-specific microRNAs (miRNAs) were generated. Similar to humans, the expression of C19MC miRNAs was mainly detected in mouse placentas. We use mouse gene expression microarrays to analyze the impact of the transgenic miRNAs on mouse placenta gene expression profiles. The transgenic mice in this study were bred to homozygocy and are referred to as dTG.

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Maternal peripheral blood natural killer cells incorporate placenta-associated microRNAs during pregnancy

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Maternal peripheral blood natural killer cells incorporate placenta-associated microRNAs during pregnancy

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