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Transcriptome profiling of NE-4C cells and NE-4C cells with knockdown of Setdb1 by RNA-sequencing

ABSTRACT: Transcriptome profiling of NE-4C cells and NE-4C cells with knockdown of Setdb1 by RNA-sequencing

PROVIDER: PRJNA791301 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR17290119_1.fastq.gz	Fastqsanger.gz
	SRR17290119_2.fastq.gz	Fastqsanger.gz
	SRR17290120_1.fastq.gz	Fastqsanger.gz
	SRR17290120_2.fastq.gz	Fastqsanger.gz

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Transcriptome profiling of NE-4C cells and NE-4C cells with knockdown of Setdb1 by RNA-sequencing

Project description:NE-4C is a mouse neural stem cell line used for study of neuronal differentiation. Setdb1 is an epigenetic modification factor responsible for catalyzing the histone modification H3K9me3. Transcription of Setdb1 gene is enriched in embryonic neural cells during vertebrate embryogenesis. Setdb1 is upregulated in cancer cells and promotes cancers. We found that knockdown of Setdb1 in NE-4C cells led to neuronal differentiation.

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Proteomic profile of NE-4C cells after radiofrequency elecromagnetic field exposure and sham-exposure

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