Project description:This study generated transcriptomic data to investigate gene expression changes in the jejunum of yak calves following enterotoxigenic Escherichia coli (ETEC) challenge and Pediococcus pentosaceus NQ0729 supplementation.
Project description:We assessed the transcriptomic adaptation of the calf rumen epithelium to changes in ruminal pH caused by feeding calf starter with and without forage during weaning transition. The calves were divided into a gorage provision group (HAY group, n = 3) and forage non-provision group (CON group, n = 4) 3 weeks after weaning.
Project description:This study generated quantitative proteomic data to investigate protein expression changes in the jejunum of yak calves following enterotoxigenic Escherichia coli (ETEC) challenge and Pediococcus pentosaceus NQ0729 supplementation. Yak calves were divided into three groups: a control group (CON), an ETEC-challenged group (ETEC), and a P. pentosaceus NQ0729-pretreated group followed by ETEC challenge (PET). Jejunal tissue samples were collected at the end of the animal trial and analyzed using LC-MS/MS-based quantitative proteomics. The dataset was used to compare protein abundance profiles among the three groups and to identify differentially expressed proteins and enriched biological pathways associated with ETEC challenge and probiotic intervention in yak calves.
Project description:Deep sequencing of mRNA from 6 organs of yak (Bos grunniens) Analysis of ploy(A)+ RNA of brain,heart,liver,lung,spleen, and stomach of yak (Bos grunniens)
Project description:<p>The yak, an economically vital species on the Qinghai-Tibet Plateau, faces a significant challenge with diarrhea during the calf stage. However, studies about diarrhea of yak calves were few. Due to the close link between diarrhea and intestinal microbiota. Therefore, this study analyzed the fecal microbiota in diarrheic and healthy yak calves, and using a pseudo germ-free (PGF) mouse model to investigate the causes for diarrhea. This study identified microbial dysbiosis in diarrheic yak calves, characterized by significant enrichment of Ruminococcus gnavus and Streptococcus.</p>
Project description:<p>This study generated metabolomic data to investigate metabolic changes in yak calves following enterotoxigenic Escherichia coli (ETEC) challenge and Pediococcus pentosaceus NQ0729 supplementation. Yak calves were divided into three groups: a control group (CON), an ETEC-challenged group (ETEC), and a P. pentosaceus NQ0729-pretreated group followed by ETEC challenge (PET). Jejunal samples were collected after the animal trial and analyzed using liquid chromatography-tandem mass spectrometry (LC-MS/MS). The dataset was used to compare metabolic profiles among the three groups and to identify metabolites and metabolic pathways associated with ETEC challenge and probiotic intervention in yak calves.</p>
2026-06-06 | MTBLS8030 | MetaboLights
Project description:ruminal microbes of yak calves
Project description:The effects of anti-lipopolysaccharide (LPS) antibody on ruminal fermentation, LPS activity, and liver transcriptomes were investigated during the subacute ruminal acidosis (SARA) challenge.
Project description:This study used yak and cattle-yak testes from different developmental stages as materials to construct a complete translation map of the testes, and integrated transcriptome and translation results to explore gene expression changes during the sexual maturation process of yak testes. This study utilized Ribo seq technology to construct a transcriptome map of yak testicular development, revealing that the expression of genes related to spermatogenesis is specifically translated and regulated at different developmental stages. In addition, many unknown open reading frames (ORFs) in the testes have been newly identified.
