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Transcriptomic analysis of donor matched primary human immature dendritic cells and monocyte-derived Langerhans cells

ABSTRACT: Transcriptomic analysis of donor matched primary human immature dendritic cells and monocyte-derived Langerhans cells

PROVIDER: PRJNA809703 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR18114779.fastq.gz	Fastqsanger.gz
	SRR18114780.fastq.gz	Fastqsanger.gz
	SRR18114781.fastq.gz	Fastqsanger.gz
	SRR18114782.fastq.gz	Fastqsanger.gz
	SRR18114783.fastq.gz	Fastqsanger.gz

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Transcriptomic analysis of donor matched primary human immature dendritic cells and monocyte-derived Langerhans cells

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Serotonin 2A Receptor Attenuates Psoriatic Inflammation by Suppressing IL-23 Secretion in Monocyte-derived Langerhans cells

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Expression data from human primary monocyte derived immature dendritic cells (iDC)

Project description:Expression data from human primary monocyte derived immature dendritic cells (iDC)

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Project description:Introduction: The interaction between the nervous and immune systems is crucial for maintaining homeostasis and can influence disease progression in inflammatory skin diseases, such as atopic dermatitis (AD). Sensory neurons in the skin can secrete neuropeptides that modulate immune cell activity, including Langerhans cells (LCs), the primary antigen-presenting cells in the epidermis. This study investigates the effects of neuropeptides on the differentiation of monocyte-derived LCs (moLCs), specifically the neuropeptides with the most profound effect, i.e. atrial- and B-type natriuretic peptides (ANP and BNP, respectively).

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Expression in donor monocyte derived cells

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