Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Influence of infection with Ascaridia galli on the chicken intestinal microbiome

PROVIDER: PRJNA830517 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR18858800_1.fastq.gz	Fastqsanger.gz
	SRR18858800_2.fastq.gz	Fastqsanger.gz
	SRR18858745_1.fastq.gz	Fastqsanger.gz
	SRR18858745_2.fastq.gz	Fastqsanger.gz
	SRR18858746_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 112

Similar Datasets

RNA-seq of the nematode Ascaridia galli exposed to flubendazole against untreated control

Project description:The aim of this study was to investigate the response in gene expression before and after exposure to the Benzimidazoles drug flubendazole in adult female Ascaridia galli worms. The nematode Ascaridia galli (order Ascaridida) is an economically important intestinal parasite responsible for increased food consumption, reduced performance, and mortality in commercial poultry production. Parasite control relies on repeated use of dewormers (anthelmintics). Benzimidazoles are currently the only anthelmintic registered against A. galli in the EU and there is an obvious risk that overuse of one drug class may lead to resistance. The worms were collected from a commercial laying hen farms before and on day three during a treatment period of 7 days with flubendazole.

2017-10-01 | E-MTAB-5705 | biostudies-arrayexpress

Proteomic profiling of the parasitic nematode Ascaridia galli

Project description:Ascaridia galli (A. galli) is one of the most common intestinal nematodes of domesticated chickens and the cause of avian ascaridiasis, a globally important disease in poultry. Its genome is sparsely sequenced and its proteome is uncharacterized. We her investigate the proteome composition in larvae and in female and male worms of A. Galli, querying the LC-MS/MS data against a hybrid database of two related nematodes; Ascaris suum and Anisakis simplex. We compare the proteome of larvae, female and male worms.

2026-05-19 | PXD072864 | Pride

Tissue-specific transcriptome regulation during intestinal nematode infection in chickens with different levels of growth performance

Project description:Co-infections with nematodes and protozoa occur frequently in free-ranging chickens and lead to complex local and systemic physiological responses, particularly in immune and metabolic pathways. This study aimed to investigate tissue-specific transcriptomic regulation in chickens co-infected with Ascaridia galli and Heterakis gallinarum, later developing a Histomonas meleagridis infection. The study focused on male birds of three chicken strains with different growth rates i.e. Lohmann Brown-LB, Lohmann Dual-LD, and Ross-308 and on three tissues; jejunum, caecum, and liver as these organs are predilection sites for the parasite life cycle, and are central in host nutrient absorption, local and systemic immune responses, and metabolic regulation.

2025-10-14 | E-MTAB-14546 | biostudies-arrayexpress

Project description:Lactic acid mediates Lactobacillus johnsonii protection against Ascaridia galli infection in chickens

| PRJNA1456382 | ENA

Anthelmintic resistance

Project description:Evaluation of benzimidazole resistance status in Ascaridia galli

| PRJEB19299 | ENA

To study the effect of moss extract as anthelmintic on cestodes and nematodes of chick and sheep

Project description:The bryophyte was collected and dried. Aqueous extract was prepared and different concentration of the extracts were treat against Ascardia galli, chicken nematode and Trichostrongylus, sheep nematode. Control was maintained for both. The control and treated samples were further processed to study the gene expression by isolating and sequencing mRNA using Illumina next-gen sequencing.

2020-09-17 | GSE137609 | GEO

Project description:Regulation Effect of Lactobacillus johnsonii on Chickens infected with Ascaridia galli

| PRJNA1378359 | ENA

Intestinal Microbiome After Gastrectomy

Project description:The gastric barrier plays a major role in the maintanance of the distal intestinal microbiome composition. It has been shown before that the use of gastric acid suppression medication, such as proton pump inhibitors, are associated with distinctive alterations of the intestinal microbiome. Foremost, the invasion of predominantly oral bacteria, like Veillonella and Streptococcus species, were a resurring finding in previous reports. Gastric cancer treatment includes the total or subtotal resection of the stomach which can influence the gastric acid production. However, the influence by alterations in gastric milieu after this treatment on the composition of the intestinal microbiome is not well studied. Therefore, the intestinal microbiome of patients after total or subtotal gastrectomy and its influence on intestinal inflammation and gut permeability will be studied.

| 2264742 | ecrin-mdr-crc

scRNAseq of small intestine-derived lamina propria CD45+ cells from untreated wild type (WT), untreated intestinal epithelial specific LSD1 knockout (cKO), antibiotic-treated WT mice and antibiotic-treated cKO mice

Project description:Mice with an intestinal epithelial specific knockout of LSD1 have changes in the intestinal epithelium including loss of Paneth and Goblet cells along with a general status of epithelial immaturity. To assess the influence of these epithelial specific changes on the mucosal immune system we performed a scRNAseq on CD45+ immune cells from the small intestine of mice with an epithelial specific LSD1 deletion (Villin-Cre+; Lsd1f/f) and wild type mice (Villin-Cre -; Lsd1f/f). To rule out a possible influence of the bacterial microbiome in the observed changes in CD45+ cell types we performed the same experiment in mice treated with antibiotics. These data allowed us to pinpoint changes in the cell populations of the mucosal immune system upon loss of LSD1 in the intestinal epithelium such as IgA producing cells and ILCs.

2023-08-02 | E-MTAB-10492 | biostudies-arrayexpress

RNA-seq of the nematode Ascaridia galli exposed to flubendazole against untreated control

Project description:RNA-seq of the nematode Ascaridia galli exposed to flubendazole against untreated control

| PRJEB20558 | ENA