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Small RNA sequencing of adipose tissue derived extracellular vesicles and hippocampus from chow- or HFD-fed male mice

ABSTRACT: Small RNA sequencing of adipose tissue derived extracellular vesicles and hippocampus from chow- or HFD-fed male mice

PROVIDER: PRJNA839751 | ENA |

REPOSITORIES: ENA

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Small RNA sequencing of adipose tissue derived extracellular vesicles and hippocampus from chow- or HFD-fed male mice

Project description:We demonstrated that adipose tissue derived extracellular vesicles from HFD-fed mice could induce cognitive impairment. miRNAs in adipose tissue-derived EVs could be transferred to the hippocampus, which promotes synaptic damage and cognitive impairment. To identify the specific subtypes of miRNAs that responsible for cognitive impairment, we examined the sRNA profiles of hippocampus and EVs extracted from adipose tissue of Chow and HFD mice by RNA deep sequencing.

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Gene expression in chow or HFD-fed OGG1-/- livers

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Genome-wide expression profile of livers from mice fed HFD,SO-HFD or Viv chow [RNAseq]

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Differential gene expression in HFD-fed mouse liver

Project description:Hepatic expression of genes in chow-fed and HFD-fed mice were compared.

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