Mus musculus
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA99069 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Expression data from embryonic stem cells differentiation
2015-08-04 | E-GEOD-58960 | ExpressionAtlas
Project description:Transcription profiling of mouse embryonic stem cell line Sox1Tv2 during neuronal differentiation
2015-11-02 | E-TABM-669 | ExpressionAtlas
Project description:Expression data from trisomy 21 and euploid induced pluripotent stem cell hematopoietic progenitors
2025-01-24 | E-GEOD-35561 | ExpressionAtlas
Project description:Transcription profiling of murine J1 embryonic stem cells undergoing a differentiation time course to study changes in transcription during stem cell differentiation
2014-08-05 | E-GEOD-3749 | ExpressionAtlas
Project description:Transcription profiling of mouse embryonic stem cell line CGR8 during differentiation to mesenchymal stem cells and then adipocyte precursors
2015-11-02 | E-TABM-668 | ExpressionAtlas
Project description:Expression data from mouse embryonic stem cell differentiation experiment
| PRJNA112617 | ENA
Project description:Global expression profiling time series of early human embryonic stem cell differentiation towards the mesoderm lineage
2025-01-23 | E-MTAB-5219 | ExpressionAtlas
Project description:Enhancer Decommissioning by LSD1 During Embryonic Stem Cell Differentiation (expression)
| PRJNA141807 | ENA
Project description:We collected whole genome testis expression data from hybrid zone mice. We integrated GWAS mapping of testis expression traits and low testis weight to gain insight into the genetic basis of hybrid male sterility.
2014-12-04 | GSE61417 | GEO
Project description:Introgressed variants from other species can be an important source of genetic variation because they may arise rapidly, can include multiple mutations on a single haplotype, and have often been pretested by selection in the species of origin. Although introgressed alleles are generally deleterious, several studies have reported introgression as the source of adaptive alleles-including the rodenticide-resistant variant of Vkorc1 that introgressed from Mus spretus into European populations of Mus musculus domesticus. Here, we conducted bidirectional genome scans to characterize introgressed regions into one wild population of M. spretus from Spain and three wild populations of M. m. domesticus from France, Germany, and Iran. Despite the fact that these species show considerable intrinsic postzygotic reproductive isolation, introgression was observed in all individuals, including in the M. musculus reference genome (GRCm38). Mus spretus individuals had a greater proportion of introgression compared with M. m. domesticus, and within M. m. domesticus, the proportion of introgression decreased with geographic distance from the area of sympatry. Introgression was observed on all autosomes for both species, but not on the X-chromosome in M. m. domesticus, consistent with known X-linked hybrid sterility and inviability genes that have been mapped to the M. spretus X-chromosome. Tract lengths were generally short with a few outliers of up to 2.7 Mb. Interestingly, the longest introgressed tracts were in olfactory receptor regions, and introgressed tracts were significantly enriched for olfactory receptor genes in both species, suggesting that introgression may be a source of functional novelty even between species with high barriers to gene flow.
| S-EPMC8784167 | biostudies-literature