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Angiogenesis plays a key role in tumor metastasis. Many genes may act in this process including formation of vessels, immune evasion,etc. Different gene expression profiles between lymphoma endothelium cells and reactive lymph node-derived endothelium cells may uncover these genes. And intensive mec...
ORGANISM(S): Homo sapiens 
ABCB5 is marker for Limbal epithilal stem cells. A comparison between ABCB5+ versus ABCB5- cultured human limbal epithelial cells was carried out to evaluate the properties of the limbal stem cell ABCB5+ with a special focus on their role in inflammation and angiogenesis.
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD041004 | Pride
Comparison of genomic expression profiles in the mesenteric lymph nodes of naturally scrapie infected (clinical and preclinical stages) and control sheep. Expression profiles comparison of 7 clinical and 4 preclinical naturally scrapie infected sheep and 6 controls.
ORGANISM(S): Ovis aries 
Background and aims: There are considerable evidences demonstrating that angiogenesis and chronic inflammation are mutually dependent. However, although cirrhosis progression is characterized with a chronic hepatic inflammatory process, this connection is not sufficiently explored as a therapeutic s...
ORGANISM(S): Rattus norvegicus 
We identified MDA-9/Syntenin (8q12) as a key component of HNSCC differentiation and angiogenesis. Robust reduction in the expression of cyclinD1, CDK4, CTNNB1, STAT3 and PI3K were evident in MDA- 9/Syntenein depleted cells, which was reversed following MDA-9/Syntenin overexpression in immortalized o...
ORGANISM(S): Homo sapiens 
According to current clinical guidelines adjuvant treatment in colon cancer is not recommended in patients with stage I and IIA, and in patients with high risk factors (IIB) adjuvant treatment has not shown a clear benefit in recurrence or survival. However, more than 20% of these patients have recu...
Lymphoma angiogenesis is orchestrated by noncanonical signaling pathways
The platelet-derived growth factor (PDGF) signaling system contributes to tumor angiogenesis and vascular remodeling. Here, we show PDGF-BB markedly induces erythropoietin (EPO) mRNA and protein expression by targeting the PDGFR-beta+ stromal and perivascular compartments. In mouse tumor models, PDG...
ORGANISM(S): Mus musculus 
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