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ProteomicsProteomic and mutant analysis of hydrogenase gene hypE in symbiotic nitrogen fixation in Mesorhizobium huakuii
Hydrogenases catalyze the simple yet importantredox reaction between protons and electrons and H2, thus, mediate interactions between microorganisms and their chemical environment. A mutation in M. huakuii hypE gene was generated by homologous recombination. The hypE mutant grew a little faster than...
ORGANISM(S): Mesorhizobium huakuii 
2023-10-24 | PXD026564 | Pride
Mesorhizobium huakuii  fmoa  antioxidant  symbiotic nitrogen fixation  proteome & mesorhizobium huakuii  hydrogenases  hype gene  symbiotic nitrogen fixation  quantitative proteomics 
ProteomicsA GMC Oxidoreductase GmcA is required for symbiotic nitrogen fixation in Rhizobium leguminosarum bv. Viciae
GmcA is a FAD-containing enzyme belonging to the GMC (glucose-methanol-choline oxidase) family of oxidoreductases. A mutation in the R. leguminosarum gmcA gene was generated by homologous recombination. The mutation in gmcA did not affect the growth of R. leguminosarum, but it displayed decreased an...
ORGANISM(S): Rhizobium leguminosarum bv. viciae 
2020-02-24 | PXD017485 | Pride
Rhizobium leguminosarum  the glucose-methanol-choline oxidoreductase gmca  symbiotic nitrogen fixation  antioxidant and symbiotic gene expression  quantitative proteomics 
TranscriptomicsNew insight into a host-pathogen interaction unveiled by transcriptomics response of the global insect pest Plutella xylostella to a fungal pathogen
A genomic insight into how an insect pest responds to the infection of a fungal insect pathogen, such as Beauveria bassiana, is critical for alternative strategy of insect pest contol based on fungal insecticides but has not been well probed. Here we constructed three pairs of digital expression lib...
ORGANISM(S): Plutella xylostella 
2016-04-06 | E-GEOD-72383 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human alveolar macrophages from phenotypically normal smokers compared to non-smokers to identify new genes linking to early events in the molecular pathogenesis of COPD
Cigarette smoking is the leading cause of the respiratory diseases collectively known as chronic obstructive pulmonary disease (COPD). While the pathogenesis of COPD is complex, there is abundant evidence that alveolar macrophages (AM) play an important role. Based on the concept that COPD is a slow...
ORGANISM(S): Homo sapiens 
2007-09-06 | E-GEOD-3212 | biostudies-arrayexpress
TranscriptomicsComparison of bone marrow-derived macrophages from BALB/c and C57BL/6 mice with and without interferon-gamma stimulation.
ABSTRACT Macrophages are essential components of the innate immune system and crucial for pathogen elimination in early stages of infection. We previously observed that bone marrow-derived macrophages (BMM) from C57BL/6 mice exhibited increased killing activity against Burkholderia pseudomallei comp...
ORGANISM(S): Mus musculus 
2014-04-15 | E-GEOD-39349 | biostudies-arrayexpress
TranscriptomicsAnalysis of gene expression changes in amyloid-beta (ADDL) and CAT-SKL antioxidant treated primary rat neuronal cells
Amyloid-beta (Aβ)-induced neurotoxicity is a major contributor to the pathologies associated with Alzheimer’s disease (AD). The formation of reactive oxygen species (ROS), and early response induced by the Aβ peptide, plays a significant role in effecting cellular pathogenesis. Here we apply a par...
ORGANISM(S): Rattus norvegicus 
2014-04-11 | E-GEOD-55369 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse lung after ventilator induced injury reveals genetic and pharmacologic evidence links oxidative stress
RATIONALE: Mechanical ventilation (MV) is an indispensable therapy for critically ill patients with acute lung injury and the adult respiratory distress syndrome. However, the mechanisms by which conventional MV induces lung injury remain unclear. OBJECTIVES: We hypothesized that disruption of the g...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9208 | biostudies-arrayexpress
TranscriptomicsMedicago truncatula roots. Nodulation vs. Arsenic
Legumes, in interaction with resistant rhizobia, combined both moderate tolerance and accumulation of metal(loids) in roots, with the ability to grow without nitrogen supply (Pajuelo et al., 2011). This quality has attracted attention for phytostabilisation of polluted soils (Reichman, 2007). Physio...
ORGANISM(S): Medicago truncatula 
2014-12-08 | E-MTAB-1723 | biostudies-arrayexpress
UnknownSymbiotic System Establishment between Piriformospora indica and Glycine max and Its Effects on the Antioxidant Activity and Ion-Transporter-Related Gene Expression in Soybean under Salt Stress.
Not available
S-EPMC9739428 | biostudies-literature
UnknownHyperthermic stress-induced increase in the expression of glutamate-cysteine ligase and glutathione levels in the symbiotic sea anemone Aiptasia pallida.
Not available
S-EPMC2732428 | biostudies-literature
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