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MetabolomicsAccumulation Characteristics of Flavonoids and Contribution to Antioxidant Capacity in Wild and Cultivated Kiwifruits

This study aimed to clarify flavonoids accumulation characteristics and their contribution to antioxidant capacity in wild type (WT) kiwifruit (Actinidia deliciosa) and three cultivated varieties (Xuxiang, XX; Yazui, YZ; Hongyang, HY). Integrating untargeted metabolomics and traditional biochemic...

2026-01-14 | MTBLS13683 | MetaboLights
MetabolomicsVariety-Specific Polyphenol Accumulation and Antioxidant Activity Differences in Apple Fruits

Oxidative stress is a key inducer of chronic diseases, and apple polyphenols exhibit significant antioxidant potential. This study systematically analyzed polyphenol accumulation characteristics and antioxidant activity of four apple cultivars (Qincui, Jiuyue Qiji, Orin, Ruixue) using a multi-lev...

2026-01-14 | MTBLS13681 | MetaboLights
MetabolomicsEffect of heat stress on serum enzyme activity, antioxidant capacity and immune parameter metabolomics datasets in Holstein cows at different growth stages

Global climate change has led to an increase in release of atmospheric CO2 and average daily temperatures, making heat stress a major challenge in dairy farming. The present study aimed to investigate metabolite changes of Holstein cows at different stages. In this experiment, 10 growing heifers,...

2022-08-11 | MTBLS5148 | MetaboLights
MetabolomicsRectal microbiomes and serum metabolomics reveal changes in serum antioxidant status and immune responses of Dezhou donkeys in late gestation to parturition

Background: Parturition is a critical event in the reproductive cycle of dairy animals, accompanied by multiple physiological changes in sex hormones, metabolism, antioxidant capacity and immune function. However, the changes in the rectal microbiota and metabolic products of Jennies from late ge...

2025-08-27 | MTBLS12897 | MetaboLights
MetabolomicsEffects of Leuconostoc lactis on the antioxidant ability and indole-3-acetaldehyde metabolism via regulating the gut microbiota-liver axis in aged laying hens

Lactobacillus has antioxidant properties that may benefit poultry production. However, there is no systematic research on antioxidant of Lactobacillus strain and its effects on regulating nutrient metabolism in aged laying hens. This study investigated the influence of Leuconostoc lactis on produ...

2025-09-09 | MTBLS12964 | MetaboLights
ProteomicsAntioxidant, Immunomodulatory and Potential Anticancer Capacity of Polysaccharides (Glucans) from Euglena gracilis G.A. Klebs
The present study was carried out to determine the bioactivity of polysaccharides extracted from Euglena gracilis (EgPs). These were characterized by FT-IR and GC-MS. Cytotoxicity analyses (MTT) were performed on healthy human gingival fibroblast cell lines (HGF-1), obtaining an IC50 of 228.66 µg mL...
ORGANISM(S): Homo sapiens (Human) 
2022-12-21 | PXD029076 | Pride
Tmt-2plex. Sulfated polysaccharides Anticancer capacity Nutraceuticals Euglena gracilis Immunomodulatory capacity Antioxidant activity 
MetabolomicsInitial exploration of the health effects on Qinghai-Tibetan Plateau yaks following short-term exposure to polystyrene microplastics: analysis of rumen microbiota, host metabolism, antioxidant function and inflammatory responses.

Abstract: Microplastics (MPs) are omnipresent in the environment, including the Qinghai-Tibet Plateau. Previous research on MPs has primarily focused on aquatic species and rodents, with little known about their impact on yaks. This study introduced yak as an animal model, employing a combin...

2026-01-17 | MTBLS13707 | MetaboLights
MetabolomicsInitial exploration of the health effects on Qinghai-Tibetan Plateau yaks following short-term exposure to polystyrene microplastics: analysis of rumen microbiota, host metabolism, antioxidant function and inflammatory responses

Microplastics (MPs) are omnipresent in the environment, including the Qinghai-Tibet Plateau. Previous research on MPs has primarily focused on aquatic species and rodents, with little known about their impact on yaks. This study introduced yak as an animal model, employing a combined analysis of ...

2026-01-17 | MTBLS13704 | MetaboLights
MetabolomicsAntioxidant Activity, Phytochemical Profiling by UPLC-QTOF-MS, and In Silico Targeting of the RNA-Binding Protein DRBD18 of Trypanosoma brucei by Bioactive Compounds from Tetradenia riparia and Tetracera poggei
Oxidative stress plays a key role in the pathogenesis of African trypanosomiasis, and plant-derived antioxidants represent a promising source of dual-action compounds capable of both scavenging reactive oxygen species and interfering with parasite survival. The present study investigates the antioxi...
2026-09-10 | MTBLS15597 | MetaboLights
TranscriptomicsNAC, Tiron and Trolox impair GBM tumorigenic cell survival by mechanisms independent from antioxidant activity
The aim of this study is to determine if, using antioxidant drugs, it is possible to interfere with the proliferative capabilities of the human glioblastoma (GBM) tumor-initiating cells (TICs). To establish which cellular processes are activated in GBM TICs by the antioxidants NAC, Tiron and Trolox,...
ORGANISM(S): Homo sapiens 
2014-03-04 | E-GEOD-44099 | biostudies-arrayexpress
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