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ProteomicsNucleosome binding by the pioneer transcription factor OCT4
The nucleosome is a fundamental unit of chromatin in eukaryotes, and generally prevents the binding of transcription factors to genomic DNA. Pioneer transcription factors overcome the nucleosome barrier, and bind their target DNA sequences in chromatin. OCT4 is a representative pioneer transcription...
ORGANISM(S): Homo Sapiens (human) 
2020-05-13 | PXD019160 | JPOST Repository
ProteomicsCold-induced urticarial autoinflammatoy syndrome related to factor XII activation
Early onset urticarial rash with systemic inflammatory symptoms are hallmarks of hereditary autoinflammatory diseases caused by gene mutations of the innate immune pathway, e.g. nucleotide receptor protein 3 (NLRP3). However, in many cases genetic tests are negative, suggesting the existence of unre...
ORGANISM(S): Homo sapiens (Human) 
2010-01-10 | PXD016341 | Pride
Cleavage Activation Factor xii 
ProteomicsACONITASE 3 is part of the ANAC017 transcription factor-dependent mitochondrial dysfunction response
Mitochondria are tightly embedded within metabolic and regulatory networks that optimize plant performance in response to environmental challenges. The best-known mitochondrial retrograde signaling pathway involves stress-induced activation of the transcription factor NAC DOMAIN CONTAINING PROTEIN 1...
ORGANISM(S): Arabidopsis Thaliana 
2022-03-14 | PXD018881 | panorama
ProteomicsThe interactome of multiprotein bridging factor 1 in Beauveria bassiana
Beauveria basiana is a well-known filamentous entomopathogenic fungus. Oxidation tolerance is an important determinant to fungal pathogenicity and biocontrol potential. B. bassiana transcriptional co-activator multiprotein bridging factor 1 (BbMBF1) contributes to fungal resistance to the oxidative ...
ORGANISM(S): Beauveria bassiana (strain ARSEF 2860) (White muscardine disease fungus) (Tritirachium shiotae) 
2017-09-11 | PXD005660 | Pride
Multiprotein bridging factor 1 Beauveria bassiana Interactome 
ProteomicsBDNF BONLAC in HEK cells
In-depth Quantitative Proteomic Analysis of De Novo Protein Synthesis Induced by Brain-derived Neurotrophic Factor
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-08-26 | MSV000078831 | MassIVE
ProteomicsMechano‐covalent protection 1 of procoagulant factor VIII by von Willebrand factor
von Willebrand factor (VWF) is the protective carrier of procoagulant factor VIII (FVIII) in the shear forces of the circulation, prolonging its half‐life and delivering it to the developing thrombus. VWF∙FVIII complex formation is characterized by catch‐bond behavior in which force first decelerat...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD034866 | Pride
Cysteines Factor fviii Von willebrand factor Disulphide bonds 
ProteomicsTranscriptomic and Proteomic Response of HC-04 to hepatocyte growth factor (HGF)
The routine study of human malaria liver-stage biology in vitro is hampered by low infection efficiency of human hepatocellular carcinoma (HCC) lines (<0.1%), poor understanding of steady-state HCC biology, and lack of appropriate tools for trace sample analysis. HC-04 is the only HCC that supports ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079959 | MassIVE
ProteomicsEarly Signaling Dynamics of EGFR
Despite extensive study of the epidermal growth factor receptor (EGFR) signaling network, the immediate post-translational changes that occur in response to growth factor stimulation remain poorly characterized; as a result, the biological mechanisms underlying signaling initiation remain obscured. ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080800 | MassIVE
ProteomicsFactor H and related proteins in AMD
Age-related macular degeneration (AMD) is a common form of adult blindness. Risk of developing AMD is strongly linked to genetics, in particular at the Regulators of Complement Activation (RCA) locus on Chr1, which contains 6 genes, Complement Factor H (CFH) and Complement Factor H-related 1-5 (CFHR...
ORGANISM(S): Homo Sapiens 
2022-01-18 | PXD023466 | panorama
ProteomicscatTFRE mass spectrometry analysis reveals transcription factor network driver of Osteosarcoma
we used the catTFRE to fish out transcription factor subpopulation of Osteosarcoma nuclear extract for mass spectrometry analysis.
ORGANISM(S): Homo sapiens (Human) 
2026-08-07 | PXD070562 | Pride
Osteosarcoma Transcription factor Cattfres 
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