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MetabolomicsCEACAM1 Targets ABCA1 to mediate Atrial Fibrillation by regulating Lipophagy-Dependent Ferroptosis

Atrial fibrillation（AF） is one of the most common arrhythmias, imposing a significant burden on individuals due to its association with cerebrovascular events. The mechanisms underlying AF involve cardiac structural remodeling, electrical remodeling, and metabolic remodeling, with oxidative ...

2025-11-12 | MTBLS13308 | MetaboLights
MetabolomicsTargeted metabolomic profiling and machine learning-based prediction models for persistent atrial fibrillation: a multi-center observational study

Background. Atrial fibrillation (AF), the most common cardiac arrhythmia worldwide, carries a high risk of severe complications. Patients diagnosed with paroxysmal atrial fibrillation (PAF) may progress to persistent atrial fibrillation (PerAF) following a period. We aimed to identify metabo...

2026-07-03 | MTBLS13136 | MetaboLights
MetabolomicsCharacterization of feces in Atrial Fibrillation (AF) patients
Not available
ORGANISM(S): Homo sapiens 
ST001208 | MetabolomicsWorkbench
TranscriptomicsHsp70 protects from stroke in atrial fibrillation patients by preventing thrombosis with no increased bleeding risk
Atrial fibrillation (AF) is a major risk factor for cardioembolic stroke. Anticoagulant drugs are effective in preventing AF-related stroke. However, the high frequency of anticoagulant-associated major bleeding is a major concern particularly when antiplatelet treatment is simultaneously administer...
ORGANISM(S): Homo sapiens 
2016-04-01 | E-GEOD-66724 | biostudies-arrayexpress
MetabolomicsAlterations in fecal metabolic patterns are associated with atrial fibrillation
Not available
ORGANISM(S): Homo sapiens 
ST001168 | MetabolomicsWorkbench
MetabolomicsAlterations in serum metabolic patterns are associated with atrial fibrillation
Not available
ORGANISM(S): Homo sapiens 
ST001169 | MetabolomicsWorkbench
ProteomicsMulti-omics analysis of plasma in atrial fibrillation patients
Comprehensive metabolomic and proteomic analyses reveal candidate biomarkers and related metabolic networks in atrial fibrillation.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-05-14 | MSV000083774 | MassIVE
TranscriptomicsRac1-Induced Connective Tissue Growth Factor regulates Connexin 43 and N-Cadherin Expression in Atrial Fibrillation
Objectives: We studied the signal transduction of atrial structural remodelling that contributes to the pathogenesis of atrial fibrillation (AF). Backround: Fibrosis is a hallmark of arrhythmogenic structural remodelling but the underlying molecular mechanisms are incompletely understood. Methods: W...
ORGANISM(S): Homo sapiens 
2010-02-21 | E-GEOD-14975 | biostudies-arrayexpress
TranscriptomicsValvular heart disease and atrial fibrillation regulate microRNA expression profiles in left and right atria differently
Background: Chronic atrial fibrillation (AF) is a complication associated with the dilated atria of patients with valvular heart disease and contributes to worsened pathology. Methods and Results: Using microarray technology, we examined microRNA (miR) expression profiles in right and left atrial ap...
ORGANISM(S): Homo sapiens 
2011-12-21 | E-GEOD-28954 | biostudies-arrayexpress
TranscriptomicsAtrial fibrillation is associated with altered left-to-right atria gene expression ratio: implications for arrhythmogenesis and thrombogenesis
Background: Atrial fibrillation (AF) causes atrial remodeling, and the left atrium (LA) is the favored substrate for maintaining AF. However, it remains unclear if AF remodels both atria differently and contributes to LA arrhythmogenesis and thrombogenesis. Results: AF was associated with differenti...
ORGANISM(S): Homo sapiens 
2016-08-09 | E-GEOD-79768 | biostudies-arrayexpress
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