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MetabolomicsMetabolome analysis reveal key regulatory pathways of feed conversion efficiency of oriental river prawn Macrobrachium nipponense

A total of 445 and 247 differently expressed metabolites (DEMs) were identified in the hepatopancreas and muscle. In addition, 11 KEGG pathways, which mainly include lysine biosynthesis, lysine degradation, aminoacyl-tRNA biosynthesis and purine metabolism, were sign...

2023-02-28 | MTBLS6663 | MetaboLights
GenomicsImpact of G-content on Arabidopsis AtPAB binding and their role in enhancing translational efficiency
Impact of G-content on Arabidopsis AtPAB binding and their role in enhancing translational efficiency
PRJNA433501 | ENA
GenomicsUPF1 ATPase autoinhibition and activation modulate RNA binding kinetics and NMD efficiency 2
UPF1 ATPase autoinhibition and activation modulate RNA binding kinetics and NMD efficiency 2
PRJNA1033187 | ENA
GenomicsUPF1 ATPase autoinhibition and activation modulate RNA binding kinetics and NMD efficiency 1
UPF1 ATPase autoinhibition and activation modulate RNA binding kinetics and NMD efficiency 1
PRJNA1033188 | ENA
GenomicsSelection for improved energy efficiency and drought tolerance in canola results in distinct transcriptome and epigenome changes [ChIP-Seq]
Integrated breeding strategies are used to increase both the yield potential and stability of crops. Most of these approaches have a direct genetic basis. The utility of epigenetics in breeding to improve complex traits such as yield and stress tolerance is not clear. A better understanding of th...
ORGANISM(S): Brassica napus 
2015-06-28 | E-GEOD-65571 | biostudies-arrayexpress
ProteomicsQuantitative proteomics of Col and AtPABs mutant
To determine if the difference in AtPAB-binding efficiency affects protein levels, we performed the Tandem Mass Tag (TMT)-based quantitative proteomics on the two-week old seedlings of Col and the mut, respectively.
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-10-11 | PXD014071 | Pride
Poly(a)-binding proteins  binding efficiency  translationa  arabidopsis 
TranscriptomicsRapid, high efficiency isolation of pancreatic ß-cells
The ability to isolate pure pancreatic ß-cells would greatly aid multiple areas of diabetes research. We developed an exendin-4-like neopeptide conjugate for the rapid purification and isolation of functional pancreatic ß-cells. By targeting the glucagon-like peptide-1 receptor, ß-cells were isolate...
ORGANISM(S): Mus musculus 
2015-09-04 | E-GEOD-64508 | biostudies-arrayexpress
TranscriptomicsmRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer
The intention was to detect genes that are determining trastuzumab efficiency in HER2-positive breast cancer cell lines with different resistance phenotypes. While BT474 should be sensitive to the drug treatment, HCC1954 is expected to be resistant due to a PI3K mutation. The cell line BTR50 has bee...
ORGANISM(S): Homo sapiens 
2015-04-21 | E-GEOD-55005 | biostudies-arrayexpress
OtherImpact of G-content on Arabidopsis AtPAB binding and their role in enhancing translational efficiency
Polyadenylation plays a key role in producing mature mRNAs in eukaryotes. It is widely believed that the poly(A)-binding proteins (PABs) uniformly bind to poly(A)-tailed mRNAs, regulating their stability and translational efficiency. Here, we characterized the RNA-binding landscape of three broadly ...
ORGANISM(S): Arabidopsis thaliana 
2019-08-14 | GSE110342 | GEO
GenomicsBenchmark study of different chromatin isolation methods using the E2Fa transcription factor
Genome-wide identification of transcription factor (TF) binding sites is pivotal to our understanding of gene expression regulation. Although much progress has been made in the determination of potential binding regions of proteins by chromatin immunoprecipitation (ChIP), this method has some inhere...
ORGANISM(S): Arabidopsis thaliana 
2014-02-04 | E-GEOD-53422 | biostudies-arrayexpress
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