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ProteomicsBrain microvessels onotogeny-INSERM ERI28
Acquired neonatal brain lesions result from the co-incidence of environment deleterious factors occurring at a specific development stage. Hypoxia-ischemia and inflammation are the major triggers of brain damage in late pregnancy and early infancy, and result in a variety of damages depending on whe...
ORGANISM(S): Mus musculus (Mouse) 
2016-01-04 | PXD001718 | Pride
Neonate Mouse Ltq-orbitrap Brain Development Microvessels 
TranscriptomicsDefining the Phosphodiesterase Superfamily Members in Rat Brain Microvessels
A filtration method followed by microarray analyses allows PDE components to be identified in brain microvessels, and confirmed that PDE4D and PDE5A are the primary forms expressed in rat brain microvessels. Adult male F344 rats were sacrificed and blocks of the cerebral cortex and infratentorial ar...
ORGANISM(S): Rattus norvegicus 
2012-02-01 | E-GEOD-35285 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of hypertensive and normotensive rats treated with the AT1 receptor antagonist candesartan and vehicle
In hypertension, abnormal regulation of microcirculation and endothelial dysfunction enhances vulnerability to hypertensive brain damage. In addition to lowering blood pressure, blockade of Angiotensin II AT1 receptors protects against stroke and stress in different animal models and this treatment ...
ORGANISM(S): Rattus norvegicus 
2007-11-03 | E-GEOD-2739 | biostudies-arrayexpress
ProteomicsTargeting mitochondria in the aged vasculature with SS-31, a proteomic study of brain microvessels.
Functional decline and structural alterations of the brain microvasculature are associated with cognitive impairment and development of dementias such as Alzheimer’s disease during aging. Although mechanisms of leading to microvascular changes during aging are not clear, the loss of mitochondria and...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-26 | PXD038483 | Pride
Brain Tmt Mitochondria Microvessels 
GenomicsGene expression profiling of the retinal microvessels and the brain microvessels
Gene expression profiling of the retinal microvessels and the brain microvessels
PRJNA434237 | ENA
TranscriptomicsRat brain microvessel SAGE
SAGE analysis of genes expressed in rat brain microvessels. Keywords: Novel gene identification Microvessels were pooled from 50 rats, a single SAGE library was constructed from the microvessel RNA
ORGANISM(S): Rattus norvegicus 
2005-12-02 | E-GEOD-3696 | biostudies-arrayexpress
TranscriptomicsBrain microvessel: Alzheimer disease vs normal
The enigma that is Alzheimer's disease (AD) continues to present daunting challenges for effective therapeutic intervention. The lack of disease-modifying therapies may, in part, be attributable to the narrow research focus employed to understand this complex disease. Most studies into disease patho...
ORGANISM(S): Homo sapiens 
2013-03-29 | E-GEOD-45596 | biostudies-arrayexpress
GenomicsBulk RNA-seq analysis of mouse brain microvessels following controlled cortical impact-induced traumatic brain injury
Bulk RNA-seq analysis of mouse brain microvessels following controlled cortical impact-induced traumatic brain injury
PRJNA1502761 | ENA
TranscriptomicsRNA-seq of brain mural cells and microvascular fragments
Purpose: Pericytes, the mural cells of blood microvessels, have come into focus as regulators of microvascular development and function, but due to paucity of defining markers, the identification and functional characterization of PC remain problematic, and reported data are often controversial. Her...
ORGANISM(S): Mus musculus 
2016-10-24 | E-GEOD-75668 | biostudies-arrayexpress
GenomicsInflammatory response of 3D brain microvessels to TNF and Plasmodium falciparum
Inflammatory response of 3D brain microvessels to TNF and Plasmodium falciparum
PRJNA946310 | ENA
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