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ProteomicsSCF dynamics regulated by CAND2
The effect of CAND2 on SCF dynamics was studied by AP-MS.
ORGANISM(S): Homo sapiens (Human) 
2025-01-20 | PXD045618 | Pride
Scf  dynamics  cand2 
Proteomicsproteome turnover assay in WT and CAND2 KO JMSU1 cells
This assay was used to assess the effect of CAND2 on global protein turnover in JMSU1 cells.
ORGANISM(S): Homo sapiens (Human) 
2025-01-20 | PXD056464 | Pride
Cand2  protein turnover 
ProteomicsSFOme in WT and CAND2 KO HEK293 cells
This assay was used to assess the SCF assembly levels in WT and CAND2 HEK293 cells.
ORGANISM(S): Homo sapiens (Human) 
2025-01-20 | PXD056462 | Pride
Scf cand2 
GenomicsCand2 links pathological mTORC1 signaling to adverse cardiac remodeling by regulating Grk5 expression
Cand2 links pathological mTORC1 signaling to adverse cardiac remodeling by regulating Grk5 expression
PRJNA642148 | ENA
UnknownMolecular mechanisms of CAND2 in regulating SCF ubiquitin ligases.
Not available
S-EPMC11865535 | biostudies-literature
TranscriptomicsCand2 links pathological mTORC1 signaling to adverse cardiac remodeling by regulating Grk5 expression
The mechanistic target of rapamycin (mTOR) is a key regulator of pathological remodeling in the heart by activating ribosomal biogenesis and mRNA translation. Inhibition of mTOR in cardiomyocytes is protective, however, a detailed role of mTOR in translational regulation of specific mRNA networks in...
ORGANISM(S): Mus musculus 
2021-07-30 | GSE153364 | GEO
ProteomicsDynamic exchange of CRL4 regulated by CAND1 and CAND2
CAND1 and CAND2 have been established as exhange factors for CRL1s, however, how they regulate the dynamic exchange of CRL4s remains not fully understood. This project aims to study and compare the effect of CAND proteins on the exchange levels of multiple DCAFs, thus providing insights into the fun...
ORGANISM(S): Homo sapiens (Human) 
2026-02-12 | PXD063817 | Pride
Silac  human  cullin-ring ubiquitin ligases 
UnknownEvaluation of CAND2 and WNT7a as candidate genes for congenital idiopathic clubfoot.
Not available
S-EPMC2664430 | biostudies-literature
UnknownDetecting epistasis within chromatin regulatory circuitry reveals CAND2 as a novel susceptibility gene for obesity.
Not available
S-EPMC6298858 | biostudies-literature
UnknownNEURL rs6584555 and CAND2 rs4642101 contribute to postoperative atrial fibrillation: a prospective study among Chinese population.
Not available
S-EPMC5173161 | biostudies-literature
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