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ProteomicsCharacterization and proteomic analysis of plasma EVs recovered from healthy and diseased dogs with Canine Leishmaniosis
Dogs are highly valued companions and work animals that are susceptible to many life-threatening conditions like canine leishmaniosis (CanL). Plasma-derived extracellular vesicles (EVs), exploited extensively in biomarker discovery, constitute a mostly untapped resource in veterinary sciences. Thus,...
ORGANISM(S): Leishmania infantum Canis familiaris (Dog) (Canis lupus familiaris) 
2023-05-10 | PXD039610 | Pride
Canine leishmaniosis  leishmania infantum  extracellular vesicles  proteomics  exosomes  leishmaniasis  leishmania  dogs  parasites 
ProteomicsHuman liver LC-MSMSProteomic research on new urinary biomarkers of renal disease in canine leishmaniosis: survival and monitoring response to treatment
The objective of our study was to search for survival biomarkers (SB) and treatment response monitoring biomarkers (TRMB) in the urinary proteome of dogs with renal disease secondardy to canine leishmaniosis (CanL),
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2023-07-20 | PXD042578 | Pride
Lc-msms Urinary proteome  canine leishmaniosis  biomarker  survival  miltefosinei.e. human Plasma Liver 
ProteomicsDDA-MS serum proteomics in dogs with leishmaniosis
Serum proteomes of healthy and Leishmania-infected dogs were analyzed by DDA-MS approach to generate sample-specific spectral library for subsequent SWATH-MS analysis, namely pooled, mixed control, mixed case (Leishmania-infected), ProteoMiner enriched, and 3 SCX fractions; all containing iRT pepti...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2023-05-10 | PXD039763 | Pride
Canine Proteomics Serum Leishmania infantum Dda 
ProteomicsDIA-MS serum proteomics in dogs with leishmaniosis
Serum proteomes of healthy and Leishmania-infected dogs were analyzed by DIA-MS approach using non-depleted serum and 60 min gradient time in order to study host response to infection.
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2023-05-10 | PXD039765 | Pride
Canine Proteomics Dia Serum Leishmania infantum 
GenomicsLeishDog: a single-cell transcriptome atlas of peripheral blood immune cells spanning progressive canine leishmaniosis
LeishDog: a single-cell transcriptome atlas of peripheral blood immune cells spanning progressive canine leishmaniosis
PRJNA1379542 | ENA
UnknownCountry-Level Canine Leishmaniosis Risk: A Literature Review, 2019-2023.
Not available
S-EPMC12414481 | biostudies-literature
UnknownRenal dialysis and long-term treatment of a dog with kidney disease associated with canine leishmaniosis.
Not available
S-EPMC5859824 | biostudies-literature
UnknownData Independent Acquisition Reveals In-Depth Serum Proteome Changes in Canine Leishmaniosis.
Not available
S-EPMC10059658 | biostudies-literature
UnknownThe first report of autochthonous non-vector-borne transmission of canine leishmaniosis in the Nordic countries.
Not available
S-EPMC4310168 | biostudies-literature
TranscriptomicsLeishDog: a single-cell transcriptome atlas of peripheral blood immune cells spanning progressive canine leishmaniosis
Controlling visceral leishmaniasis (VL) requires not only addressing human disease but also targeting animal reservoirs, particularly domestic dogs, which are critical hosts that sustain zoonotic Leishmania infantum transmission. Although considerable advances have been made, the immune mechanisms u...
ORGANISM(S): Canis lupus familiaris 
2026-05-21 | GSE313451 | GEO
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