Sort   by:  
 Page size 
MetabolomicsCiprofloxacin-induced metabolic disruption and stringent response drives persistent small-colony variants in Staphylococcus aureus

Antibiotic treatment failure in Staphylococcus aureus infections is frequently associated with antimicrobial resistance or the emergence of small-colony variants (SCVs), a metabolically quiescent phenotype that complicates infection management. Here, we show that ciprofloxacin induces a stable SC...

2025-11-19 | MTBLS13343 | MetaboLights
MetabolomicsLsr2, a novel cyclic di-GMP receptor, regulate the synthesis of keto-mycolic acid and control biofilm formation in mycobacteria

Cyclic di-GMP (c-di-GMP) is a well-known second messenger that plays a key role in many physiological processes in bacteria. The synthesis of lipids is essential for bacterial biofilm formation. However, whether c-di-GMP signaling modulates the synthesis of lipid and further regulates biofilm for...

2023-12-12 | MTBLS7053 | MetaboLights
ProteomicsElucidating colony bloom formation mechanism of a harmful alga Phaeocystis globosa (Prymnesiophyceae) using metaproteomics
Phaeocystis is a globally distributed Prymnesiophyceae genus and usually forms massive harmful colony blooms, which impact marine ecosystem, mariculture, human health, and even threaten coastal nuclear power plant safety. However, the mechanisms behind the colony formation from the solitary cells re...
ORGANISM(S): Phaeocystis globosa 
2023-02-10 | PXD035588 | Pride
Phaeocystis globosa  harmful colony bloom  colony formation  glycosaminoglycan biosynthesis  metaproteomics 
TranscriptomicsGene expression of E. coli MG1655 at attachment, colony formation and maturation during biofilm formation
Gene expression changes during biofilm formation processes were investigated. The gene expression was compared at attachment, colony formation and maturation during biofilm formation. At the same time, the gene expressions were also compared with exponential phase and stationary phase in planktonic ...
ORGANISM(S): Escherichia coli 
2009-04-01 | E-GEOD-13418 | biostudies-arrayexpress
ProteomicsThe mechanism of infochemicals induced colony formation and flocculation in the microalga Scenedesmus subspicatus
Daphnia infochemicals can induce defensive responses in microalgae Scenedesmus spp., including colony formation and flocculation. We investigated the phenomenon using a combination of microalgal biology, physiological ecology, and quantitative isobaric tagging (iTRAQ) proteomics. We have discovered ...
ORGANISM(S): Desmodesmus subspicatus 
2020-05-06 | PXD014153 | Pride
Daphnia infochemicals Scenedesmus Induced defences Colony formation itraq proteomics Flocculation Predation 
TranscriptomicsIdentification of a complex genetic network involved in Saccharomyces cerevisiae colony morphology
When grown on solid substrates, different microorganisms often form colonies with very specific morphologies. Whereas the pioneers of microbiology often used colony morphology to discriminate between species and strains, the phenomenon has not received much recent attention. In this study, we use ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-04-27 | E-GEOD-36151 | biostudies-arrayexpress
TranscriptomicsDifferential Gene Expression and Clonal Selection during Cellular Transformation Induced by Adhesion Deprivation (A16 vs COLONY)
Cell substrate adhesion plays an important role in cellular transformation of rat fibroblast cell lines, however a few viable non-adherent fibroblast cells when placed in suspension for a time period of 16 h (NA16) showed varied phenotypic characteristics like colony and tumor formation In order to ...
ORGANISM(S): Rattus norvegicus 
2010-11-14 | E-GEOD-24878 | biostudies-arrayexpress
GenomicsSingle-cell RNA sequencing of C3(1)-Tag cancer cells during invasion and colony formation.
Single-cell RNA sequencing of C3(1)-Tag cancer cells during invasion and colony formation.
PRJNA627920 | ENA
ProteomicsA novel variant of Salmonella enterica serovar Typhimurium with a rough colony morphology and multidrug resistance
Salmonella enterica serovar Typhimurium (S. Typhimurium) is a major cause of salmonellosis, with various multidrug-resistant pathovariants emerging. Here, we investigated a distinct rough colony variant with potentially enhanced environmental adaptation in China. Whole-genome sequencing of 2,212 Chi...
ORGANISM(S): Salmonella Enterica Subsp. Enterica Serovar Typhimurium Str. Lt2 
PXD047483 |
TranscriptomicsGene expression of E. coli MG1655 at attachment, colony formation and maturation during biofilm formation
Gene expression changes during biofilm formation processes were investigated. The gene expression was compared at attachment, colony formation and maturation during biofilm formation. At the same time, the gene expressions were also compared with exponential phase and stationary phase in planktonic ...
ORGANISM(S): Escherichia coli Escherichia coli K-12 
2009-04-01 | GSE13418 | GEO
Sort   by:  
 Page size