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ProteomicsDysregulation of the complement and coagulation cascade in treated schizophrenia and bipolar disorder patients
A better understanding of the proteomic profile after bipolar disorder (BD) and schizophrenia (SCZ) treatment, through monitoring its progression, may assist the development of novel therapeutic strategies with the ability to reduce or control possible side effects. In this study, proteomics analysi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-11-07 | MSV000086425 | MassIVE
GenomicsValproic acid attenuates hyperglycemia induced complement and coagulation cascade gene expression
Valproic acid attenuates hyperglycemia induced complement and coagulation cascade gene expression
PRJNA429757 | ENA
ProteomicsProteomics analysis of plasma-derived exosomes unveils the aberrant complement and coagulation cascades in dermatomyositis/polymyositis
Dermatomyositis and polymyositis (DM/PM) are systemic autoimmune diseases characterized by proximal muscle weakness. The underlying pathogenetic mechanism of this disease remains elusive. Here, using proteomics analysis, a great overlap of differentially expressed plasma exosomal proteins involved i...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD037608 | Pride
Dermatomyositis  polymyositis  exosomes  proteomics  complement and coagulation cascades. 
ProteomicsProteomics analysis of plasma-derived exosomes unveils the aberrant complement and coagulation cascades in dermatomyositis/polymyositis
Dermatomyositis and polymyositis (DM/PM) are systemic autoimmune diseases characterized by proximal muscle weakness. The underlying pathogenetic mechanism of this disease remains elusive. Here, using proteomics analysis, a great overlap of differentially expressed plasma exosomal proteins involved i...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD037483 | Pride
Dermatomyositis  polymyositis  exosomes  proteomics  complement and coagulation cascades. 
UnknownCoagulation cascade and complement system in systemic lupus erythematosus.
Not available
S-EPMC5871083 | biostudies-literature
ProteomicsBlood coagulation and complement activation interact to increase disease activity in systemic lupus erythematosus and coagulation D-Dimer combined with complement C4 is a biomarker of lupus activity
This study was conducted to (1) find deregulation of certain pathways in SLE at multi-omics levels; (2) evaluate the associations among blood coagulation, complement activation, inflammatory responses and SLE disease severity; (3) develop biomarkers to facilitate better the assessment of the likelih...
ORGANISM(S): Homo sapiens (Human) 
2018-10-27 | PXD004443 | Pride
Systemic lupus erythematosus  blood coagulation itraq 
ProteomicsN-terminomics profiling of host proteins targeted by excretory-secretory proteases of the nematode Angiostrongylus vasorum identifies points of interaction with canine coagulation and complement cascade
The cardiopulmonary nematode Angiostrongylus vasorum can cause severe disease in dogs, including coagulopathies manifesting with bleeding. We analysed A. vasorum excretory/secretory protein (ESP)-treated dog plasma and serum by N-terminome analysis using Terminal Amine Isotopic Labelling of Substrat...
ORGANISM(S): Angiostrongylus vasorum Canis familiaris (Dog) (Canis lupus familiaris) 
2025-05-07 | PXD056659 | Pride
Dog Serum French heartworm Plasma Tails 
TranscriptomicsValproic acid attenuates hyperglycemia induced complement and coagulation cascade gene expression
Diabetes is a multifactorial disorder and epigenetics changes are increasingly appreciated to influence the development of diabetic complications. Chromatin remodeling and histone acetylation are implicated in activation of the inflammatory response. Recently, histone deacetylase (HDAC) inhibitors (...
ORGANISM(S): Homo sapiens 
2018-01-13 | GSE109140 | GEO
UnknownIn silico and in vitro studies reveal complement system drives coagulation cascade in SARS-CoV-2 pathogenesis.
Not available
S-EPMC7657020 | biostudies-literature
UnknownVitamin D3 improved hypoxia-induced lung injury by inhibiting the complement and coagulation cascade and autophagy pathway.
Not available
S-EPMC10759436 | biostudies-literature
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