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ProteomicsProteomic Analyses of Plasma from Patients with Fracture Related Infection Reveals Systemic Activation of the Complement and Coagulation Cascades
Patients/Participants: Twenty-seven patients meeting confirmatory FRI criteria were matched to 27 controls based on fracture region, age, and time after surgery Intervention: Tandem Mass Tag (TMT) LC-MS analysis of patient plasma samples Main Outcome Measurements: Abundances for over 1000 proteins w...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-10-15 | MSV000093116 | MassIVE
ProteomicsProteomics analysis of plasma-derived exosomes unveils the aberrant complement and coagulation cascades in dermatomyositis/polymyositis
Dermatomyositis and polymyositis (DM/PM) are systemic autoimmune diseases characterized by proximal muscle weakness. The underlying pathogenetic mechanism of this disease remains elusive. Here, using proteomics analysis, a great overlap of differentially expressed plasma exosomal proteins involved i...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD037608 | Pride
Dermatomyositis  polymyositis  exosomes  proteomics  complement and coagulation cascades. 
ProteomicsProteomics analysis of plasma-derived exosomes unveils the aberrant complement and coagulation cascades in dermatomyositis/polymyositis
Dermatomyositis and polymyositis (DM/PM) are systemic autoimmune diseases characterized by proximal muscle weakness. The underlying pathogenetic mechanism of this disease remains elusive. Here, using proteomics analysis, a great overlap of differentially expressed plasma exosomal proteins involved i...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD037483 | Pride
Dermatomyositis  polymyositis  exosomes  proteomics  complement and coagulation cascades. 
ProteomicsDysregulation of the complement and coagulation cascade in treated schizophrenia and bipolar disorder patients
A better understanding of the proteomic profile after bipolar disorder (BD) and schizophrenia (SCZ) treatment, through monitoring its progression, may assist the development of novel therapeutic strategies with the ability to reduce or control possible side effects. In this study, proteomics analysi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-11-07 | MSV000086425 | MassIVE
ProteomicsNafamostat Mesilate Improves Sepsis Outcomes by Modulating Complement and Coagulation Pathways
Supporting data for: Nafamostat Mesilate Improves Sepsis Outcomes by Modulating Complement and Coagulation Pathways
ORGANISM(S): Homo Sapiens 
2026-02-24 | PXD074871 |
ProteomicsAvian pathogenic Escherichia coli infection causes infiltration of heterophilic granulocytes of chick tracheal by the complement and coagulation cascades pathway
Tracheal mucosal epithelial cells were scraped at 12 and 24 hours of infection, frozen in liquid nitrogen and stored at -80°C. The cells were sent to a biotechnology company for TMT quantitative proteomic analysis. The cells were sent to a biotech company for TMT quantitative proteomics analysis.
ORGANISM(S): Gallus gallus (Chicken) 
2024-01-26 | PXD044411 | Pride
Avian pathogenic escherichia coli  ae17  tmt-sequencing  complement and coagulation cascades pathways  pathogenicity 
ProteomicsProteomics profiling of vitreous humor reveals complement and coagulation components, adhesion factors, and neurodegeneration markers as discriminatory biomarkers of vitreoretinal eye diseases
Diabetic retinopathy (DR) and age-related macular degeneration (AMD) are leading causes of visual impairment and blindness in people aged 50 years or older in middle-income and industrialized countries. Anti-VEGF therapies have improved the management of neovascular AMD (nAMD) and proliferative DR (...
ORGANISM(S): Homo sapiens (Human) 
2023-03-09 | PXD038285 | Pride
Complement and coagulation cascades Age-related macular degeneration Neurodegeneration Vitreous proteomics. Extracellular matrix Proliferative diabetic retinopathy Biomarkers Retinal detachment 
ProteomicsProteomic analysis of lysine 2-hydroxyisobutyryl in SLE reveals protein modification alteration in Complement and coagulation cascades and Platelet activation pathways
Post-translational modifications (PTMs) are considered to be an important factor in the pathogenesis of SLE. Lysine 2-hydroxyisobutyryl (Khib), as an emerging post-translational modification of proteins, is involved in some important biological metabolic activities. We compared the Khib levels of SL...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD040218 | Pride
Human Lysine 2-hydroxyisobutyryl Pbmc Sle 
UnknownThe Complement and Coagulation Cascades Pathway is Associated with Acute Necrotizing Pancreatitis by Genomics and Proteomics Analysis.
Not available
S-EPMC9014310 | biostudies-literature
UnknownMASPs at the crossroad between the complement and the coagulation cascades - the case for COVID-19.
Not available
S-EPMC7982787 | biostudies-literature
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