cpg methylation

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Unknown (7477)
Genomics (3335)
Transcriptomics (1573)
Methylation profiling (1381)
Proteomics (145)
Other (42)
Genomic (10)
Clinical (4)
Metabolomics (2)

Organisms

Homo sapiens (2603)
Mus musculus (1003)
Arabidopsis thaliana (62)
Rattus norvegicus (52)
Danio rerio (31)
Bos taurus (30)
Gallus gallus (15)
Sus scrofa (14)
Saccharomyces cerevisiae (13)
Macaca mulatta (11)
Apis mellifera (9)
Drosophila melanogaster (9)
Canis lupus familiaris (8)
Taeniopygia guttata (7)
Caenorhabditis elegans (6)
Camponotus floridanus (3)
Harpegnathos saltator (3)
Glycine max (3)
Oryza sativa Japonica Group (3)
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Sminthopsis crassicaudata (2)
Nasonia vitripennis (2)
Pan troglodytes troglodytes (2)
Schistocerca gregaria (2)
Gorilla gorilla gorilla (2)
Pongo pygmaeus (2)
Nasonia giraulti (1)
Trichinella spiralis (1)
Arabidopsis lyrata (1)
Aspergillus nidulans (1)

Organisms

Homo sapiens (1462)
Mus musculus (549)
Rattus norvegicus (22)
Arabidopsis thaliana (21)
Bos taurus (16)
Danio rerio (15)
Sus scrofa (8)
Gallus gallus (7)
Taeniopygia guttata (5)
synthetic construct (4)
Canis lupus familiaris (4)
Solanum lycopersicum (4)
Cricetulus griseus (3)
Macaca mulatta (3)
Saccharomyces cerevisiae (3)
Equus caballus (3)
Oryzias latipes (3)
Diuraphis noxia (2)
Heterocephalus glaber (2)
Dicentrarchus labrax (2)
Fundulus heteroclitus (2)
Tribolium castaneum (2)
Mus musculus musculus (2)
Drosophila melanogaster (2)
Ovis aries (2)
Taenia solium (1)
Thymallus thymallus (1)
Psammomys obesus (1)
Morone saxatilis (1)
Picochlorum sp. 'soloecismus' (1)

Repository

ENA (2530)
geo (2125)
biostudies-arrayexpress (1572)
EGA (108)
PeptideAtlas (95)
pride (27)
MassIVE (13)
dbGaP (10)
jPOST (4)
MetaboLights (2)
NODE (2)

Tissue

Digestive System (95)
Cell culture (8)
Embryonic stem cell (5)
Epithelial cell (4)
Villi (2)
Brain (2)
Blood (1)
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Colon epithelial cell (1)
Embryo (1)
Kidney (1)
Leaf (1)
Liver (1)
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Myoblast differentiation (1)
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Type B pancreatic cell (1)
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Disease

Normal (5)
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Melanoma (2)
Colon cancer (2)
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Malignant mesothelioma (1)
Breast Carcinoma (1)
Phyllodes tumor (1)
Oligodendroglioma (1)
Infiltrating ductal carcinoma (1)
Primary tumor (1)
Ganglioneuroblastoma (1)
Not yet visible (1)
Adrenocortical Adenoma (1)
Colorectal cancer (1)
Osteosarcoma (1)
Colon carcinoma (1)
NGT (1)
Glioblastoma multiforme (1)
Temporal lobe epilepsy (1)
Non-small cell lung cancer (1)
Acute promyelocytic leukemia (1)
Gastric cancer (1)
Colorectal adenocarcinoma (1)
Prostate cancer (1)
Breast carcinoma (1)
Breast cancer (1)
Neoplasms (1)
Brain cancer (1)
Cervix carcinoma (1)

Technology Type

Mass Spectrometry (27)
Shotgun proteomics (12)
Affinity purification coupled with mass spectrometry proteomics (9)
Data-independent acquisition (4)
DiaPASEF (4)
Bottom-up proteomics (3)
Illumina HiSeq 2000 (2)
Illumina Genome Analyzer II (2)
SWATH MS (2)
Illumina HiSeq 2000, HiSeq X Ten, Illumina HiSeq 2500, ILLUMINA (1)
ILLUMINA, HiSeq X Ten (1)
Illumina HiSeq 4000, ILLUMINA (1)
Illumina HumanMethylation450 (1)
Illumina HiSeq 2500, ILLUMINA (1)
ILLUMINA, Illumina HiSeq 2500 (1)
Illumina 450K, Bisulfite-Seq (1)
Illumina 450K (1)
Illumina 450k (1)
Illumina Infinium HumanMethylation450 BeadChips (1)
Illumina_450K (1)
GeneChip HTA 2.0 (1)
Illumina HiSeq 2500 (1)
Unknown (1)
Illumina MiSeq (1)
Illumina HiSeq 2000, ILLUMINA (1)
NMR spectroscopy (1)
Mass spectrometry (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)
Data-dependent acquisition (1)

Instrument Platform

Illumina HiSeq 2000 (19)
Illumina NovaSeq 6000 (15)
Illumina HiSeq 2500 (11)
Illumina MiSeq (7)
Illumina Genome Analyzer II (6)
Illumina HiSeq 4000 (6)
NextSeq 2000 (5)
NextSeq 500 (5)
PromethION (4)
Illumina Genome Analyzer IIx (3)
Illumina NovaSeq X (3)
HiSeq X Ten (3)
Qubit (2)
GenePix 4000B [Axon Instruments] (2)
Institutional high-performance computing cluster (Linux-based) (1)
PCR (1)
Centrifuge (1)
Incubator, Centrifuge (1)
Element AVITI (1)
Covaris (1)
Illumina Genome Analyzer Iix (1)
Ilumina HiScan H166 (1)
Covaris S220 (LGC Genomics GmbH), Bioanalyseur 2100 (Agilent), Bravo Platform (Agilent) (1)
GenePix 4000B Microarray Scanner (Molecular Devices). (1)
IScan Illumina (1)
Galaxy Server (1)
Scanning of was performed on an Axon 4000B scanner (1)
X86_64-apple-darwin13.4.0 (64-bit) (1)
Qiagen MinElute (1)
Illumina iScan (1)

Publication Date

2014 (496)
2013 (389)
2015 (338)
2012 (289)
2011 (258)
2016 (229)
2025 (182)
2017 (176)
2020 (168)
2010 (167)
2023 (157)
2026 (152)
2019 (149)
2024 (145)
2021 (141)
2018 (122)
2022 (117)
2009 (68)
2008 (51)
2007 (21)
2006 (7)
2005 (6)

UNIPROT ID/AC

A0A024RC46 (95)
A0A087WTX5 (95)
A0A087WVW2 (95)
A0A087WXI0 (95)
A0A087WYL9 (95)
A0A087X130 (95)
A0A087X1V9 (95)
A0A0A0MS07 (95)
A0A0A0MS51 (95)
A0A0B4J1V0 (95)
A0A0C4DG89 (95)
A0AVT1 (95)
A0FGR8 (95)
A0FGR8-2 (95)
A0FGR8-6 (95)
A0M8Q6 (95)
A0N5G5 (95)
A1L0T0 (95)
A2BFH1 (95)
A2IPI2 (95)
A2IPI5 (95)
A2NB46 (95)
A2NKM6 (95)
A2NUT2 (95)
A2NXP9 (95)
A4F255 (95)
A5A3E0 (95)
A6NHL2 (95)
A6NNZ2 (95)
A8MTJ3 (95)

ENSEMBL ID

ENSG00000170477 (95)
ENSG00000229353 (47)
ENSG00000147251 (18)
ENSG00000176092 (2)
ENSG00000247315 (1)

CHEBI ID

CHEBI:27570 (2)
CHEBI:18186 (2)
CHEBI:17234 (2)
CHEBI:28300 (2)
CHEBI:24898 (2)
CHEBI:25017 (2)
CHEBI:28044 (2)
CHEBI:27266 (2)
CHEBI:16704 (2)
CHEBI:15891 (2)
CHEBI:18237 (2)
CHEBI:15727 (2)
CHEBI:17568 (2)
CHEBI:32816 (2)
CHEBI:78320 (2)
CHEBI:15428 (2)
CHEBI:18012 (2)
CHEBI:16449 (2)
CHEBI:17154 (2)
CHEBI:16919 (2)
CHEBI:17596 (2)
CHEBI:17368 (2)
CHEBI:30769 (2)
CHEBI:57306 (1)
CHEBI:72821 (1)
CHEBI:89577 (1)
CHEBI:73005 (1)
CHEBI:133225 (1)
CHEBI:58451 (1)
CHEBI:29679 (1)

Metabolite Name

Asparatate (1)
2-hydroxylignocerate (1)
2-hydroxyquinoline (1)
1-methylhypoxanthine (1)
11-dehydrocorticosterone (1)
Adenosine diphosphate (1)
7-ketolithocholate (1)
3-(2-hydroxyphenyl)propionate (1)
Taurolithocholate (1)
4-hydroxyphenylacetylglycine (1)
Sphingomyelin (d18:2/18:1) (1)
P-cresol glucuronide (1)
Mannonate (1)
Homostachydrine (1)
Argininate (1)
2-hydroxyarachidate (1)
1-palmitoyl-2-oleoyl-GPI (16:0/18:1) (1)
1-linoleoyl-GPI (18:2) (1)
3beta,7alpha-dihydroxy-5-cholestenoate (1)
Trizma acetate (1)
Gamma-tocotrienol (1)
Alpha-tocotrienol (1)
5-methylthioribose (1)
Nicotinamide adenine dinucleotide (1)
Glycerophosphoserine (1)
Glycerophosphoinositol (1)
Alpha-ketoglutaramate (1)
2-palmitoleoyl-GPC (16:1) (1)
1-stearoyl-2-docosahexaenoyl-GPE (18:0/22:6) (1)
1-palmitoyl-2-docosahexaenoyl-GPE (16:0/22:6) (1)

First Public Date

2014 (463)
2024 (212)
2025 (193)
2023 (189)
2019 (178)
2017 (175)
2026 (171)
2020 (169)
2021 (160)
2015 (136)
2022 (135)
2013 (133)
2018 (121)
2016 (87)
2012 (5)
2011 (3)

Study status

Enrolling by invitation (1)
Active, not recruiting (1)
Recruiting (1)
Completed (1)

Lab affiliation

Department of Cell & Developmental Biology, University of California, San Diego, CA 92093, USA. (3)
Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, Netherlands (1)
CNRS UMR7242, Biotechnology and Cell Signaling, University of Strasbourg, 300 Bd Sébastien Brant, 67412 Illkirch, France (1)
Cambridge Centre for Proteomics, Department of Biochemistry, University of Cambridge, Cambridge, CB2 1QR UK (1)
Cancer Epigenetics Group, Josep Carreras Leukaemia Research Institute, 08916, Badalona, Barcelona, Catalonia, Spain. (1)
Cancer Epigenetics Group, Josep Carreras Leukaemia Research Institute, 08916, Badalona, Barcelona, Catalonia, Spain (1)
Center for Epigenetics Van Andel Research Institute Grand Rapics, Michigan 49503, USA (1)
Cleveland Clinic (1)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States (1)
Department of Cellular & Molecular Medicine, University of California, San Diego, CA 92093, USA. (1)
Department of Genome Regulation, Max Planck Institute for Molecular Genetics; Berlin, Germany (1)
Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, the Netherlands (1)
Department of Neurology, University Hospital and University of Zurich (1)
Department of Pathology and Immunology Washington University School of Medicine (1)
EDyP (1)
Facility - Proteomics & Metabolomics (1)
Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland (1)
Institute for Clinical Chemistry and Pathobiochemistry, Department for Diagnostic Laboratory Medicine, University Hospital Tübingen, Hoppe-Seyler-Str. 3 72076 Tübingen, Germany (1)
Institute of Biochemistry, ETH Zurich (1)
Max Planck Institute for Molecular Genetics Department of Genome Regulation Ihnestraße 63-73 14195 Berlin, Germany (1)
Molecular Biology, Radboud Institute for Molecular Life Sciences (RIMLS), Nijmegen, the Netherlands (1)
Radboud University, Department of Molecular Developmental Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, 6500 HB Nijmegen, The Netherlands (1)
The University of Tokyo (1)
University of Edinburgh (1)
University of Southampton (1)

Keyword

Molecular biology (1)
Sessile serrated polyp (1)
Plasma (1)
Blood (1)
Prevalence (1)
Biomarker (1)
Screening (1)

Classification

viruses (2)
helminths (1)
protozoa (1)

Modification

N6 (1)

Study type

Methylation profiling by array (592)
Methylation profiling by high throughput sequencing (340)
Transcription profiling by array (303)
ChIP-seq (115)
RNA-seq of coding RNA (104)
ChIP-chip by tiling array (18)
Bisulfite-seq (17)
Comparative genomic hybridization by array (14)
ChIP-chip by array (10)
Other (10)
Unknown experiment type (8)
DNA-seq (8)
RNA-seq of non coding RNA (7)
Genotyping by array (5)
Human - Methylation microarray (3)
Cell line - High-throughput sequencing (2)
MBD-seq (2)
Transcription profiling by SAGE (1)
Cell line - Methylation microarray (1)
Cell line - Two-color microarray (1)
Animal - One-color microarray (1)
Animal - Single-cell sequencing (1)
Human - High-throughput sequencing (1)
High-throughput sequencing (1)
Human - One-color microarray (1)
Transcription profiling by tiling array (1)
RNAi profiling by array (1)
MicroRNA profiling by high throughput sequencing (1)
MicroRNA profiling by array (1)
RNA-seq of coding RNA from single cells (1)

Release Date

2014 (686)
2022 (666)
2015 (657)
2020 (600)
2021 (587)
2013 (572)
2016 (553)
2019 (545)
2017 (526)
2023 (520)
2025 (491)
2018 (469)
2024 (460)
2012 (419)
2011 (356)
2010 (308)
2009 (135)
2008 (133)
2026 (86)
2007 (75)
2006 (52)
2005 (31)
2004 (25)
2002 (24)
2003 (23)
2001 (19)
1999 (15)
1998 (7)
2000 (6)
1997 (2)

Location

Hungary (1)
South Korea (1)
Spain (1)
China (1)
Germany (1)

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DNA methylation distinguishes pathologically normal human tissues

Epigenetic control of gene transcription is critical for normal human development and cellular differentiation. While alterations of epigenetic marks such as DNA methylation have been linked to cancers and many other human diseases, interindividual epigenetic variation in normal tissues due to aging...

ORGANISM(S): Homo sapiens

2010-06-25 | E-GEOD-19434 | biostudies-arrayexpress

Global, comparative analysis of tissue-specific promoter CpG methylation.

Understanding cell-type-specific epigenetic codes on a global level is a major challenge after the sequencing of the human genome has been completed. Here we applied methyl-CpG immunoprecipitation (MCIp) to obtain comparative methylation profiles of coding and noncoding genes in three human tissues,...

ORGANISM(S): Homo sapiens

2007-08-07 | E-GEOD-5548 | biostudies-arrayexpress

Comparative methylomics reveals gene-body H3K36me3 in Drosophila predicts DNA methylation and CpG landscapes in other invertebrates

Here, we demonstrate that Nematostella vectensis, Ciona intestinalis, Apis mellifera, and B. mori, show two distinct populations of genes differentiated by gene-body CpG density. Genome-scale DNA methylation profiles for A. mellifera spermatozoa reveal CpG-poor genes are methylated in the germ line,...

ORGANISM(S): Apis mellifera

2011-06-16 | E-GEOD-29982 | biostudies-arrayexpress

CpG site methylation of HCV-cirrhotic, HCV-HCC, and normal liver tissues

In this study we used a high-throughput method for assaying methylation of CpG sites simultaneously in a single sample for identifying differences in methylation observed in tissues ranging from normal liver to pre-neoplastic (cirrhosis) and neoplastic (HCC) states. Since there are important clinica...

ORGANISM(S): Homo sapiens

2010-02-18 | E-GEOD-18081 | biostudies-arrayexpress

Detection of aberrant DNA methylation in AML cell lines compared to normal human monocytes

To globally define methylation-â€™proneâ€™ and -â€™protectedâ€™ CpG islands in leukemia, we analyzed the methylation status of 23,000 CpG islands of the human genome in two acute leukemia cell lines as well as normal blood monocytes using our previously described methyl-CpG immunoprecipitation (MCIp...

ORGANISM(S): Homo sapiens

2010-06-05 | E-GEOD-17455 | biostudies-arrayexpress

Lung adenocarcinoma and mesothelioma DNA methylation

Pathologic differentiation of tissue of origin in tumors found in the lung can be challenging, with differentiation of mesothelioma and lung adenocarcinoma emblematic of this problem. Indeed, proper classification is essential for determination of treatment regimen for these diseases, making accurat...

ORGANISM(S): Homo sapiens

2010-06-25 | E-GEOD-16559 | biostudies-arrayexpress

Detection of aberrant DNA methylation in acute leukemia samples compared to normal human monocytes

To globally define methylation-â€™proneâ€™ and -â€™protectedâ€™ CpG islands in leukemia, we analyzed the methylation status of 23,000 CpG islands of the human genome in eight acute leukemia samples as well as normal blood monocytes using our previously described methyl-CpG immunoprecipitation (MCIp)...

ORGANISM(S): Homo sapiens

2010-06-05 | E-GEOD-17510 | biostudies-arrayexpress

Detection of aberrant DNA methylation in colorectal carcinoma samples compared to normal human colon

To globally define methylation-â€™proneâ€™ and -â€™protectedâ€™ CpG islands in colorectal carcinoma we analyzed the methylation status of 23,000 CpG islands of the human genome in ten coleorectal carcinoma samples as well as normal colon using our previously described methyl-CpG immunoprecipitation ...

ORGANISM(S): Homo sapiens

2010-06-05 | E-GEOD-17512 | biostudies-arrayexpress

Methylation orofiling of human stem cell reprogramming by targeted bisulfite sequencing

We report a method for specific capture of an arbitrary subset of genomic targets for single molecule bisulfite sequencing, and for digital quantitation of DNA methylation at a single nucleotide resolution. We used targeted bisulfite sequencing to characterize the changes of DNA methylation during t...

ORGANISM(S): Homo sapiens

2009-08-28 | E-GEOD-15007 | biostudies-arrayexpress

TET1 is a maintenance DNA demethylase that prevents methylation spreading in adult cells [DREAM]

We report that full length TET1 (TET1-FL) overexpression fails to induce global DNA demethylation in HEK293T cells. The preferential binding of TET1-FL to hypomethylated CpG islands (CGIs) through its CXXC domain leads to its inhibited 5-hydroxymethylcytosine (5hmC) production as methylation level i...

ORGANISM(S): Homo sapiens

2014-06-04 | E-GEOD-44038 | biostudies-arrayexpress

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