differential solubility

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Aerococcus urinae NBRC 15544 = CCUG 36881 (23)
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Organisms

Methylobacterium nodulans ORS 2060 (1)
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Homo sapiens (1)

Repository

biostudies-arrayexpress (25)
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Disease

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Dilated cardiomyopathy (1)
Senile cataract (1)
Systolic heart failure (1)

Technology Type

Mass Spectrometry (23)
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Data-dependent acquisition (4)
Mass spectrometry (3)
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Gel-based experiment (1)
SRM/MRM (1)
SWATH MS (1)

Instrument Platform

Agilent High resolution C scanner (2)
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RNeasy 96-well plate kit (1)
ScanArray 5000 [PerkinElmer] (1)
None (1)
NextSeq 2000 (1)
Flow injection analysis MS - negative (1)
Flow injection analysis MS - positive (1)
Liquid Chromatography MS - positive - hilic (1)
Liquid Chromatography MS - positive - reverse phase (1)
Liquid Chromatography MS - negative - reverse phase (1)

Publication Date

2026 (7)
2008 (6)
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2013 (2)
2012 (2)
2009 (2)
2006 (2)
2005 (2)
2018 (2)
2014 (1)
2019 (1)
2017 (1)

UNIPROT ID/AC

P37840 (1)
8030.ENSSSAP00000000096 (1)
8030.ENSSSAP00000000573 (1)
8030.ENSSSAP00000001022 (1)
8030.ENSSSAP00000001240 (1)
8030.ENSSSAP00000001597 (1)
8030.ENSSSAP00000001915 (1)
8030.ENSSSAP00000002059 (1)
8030.ENSSSAP00000002148 (1)
8030.ENSSSAP00000002253 (1)
8030.ENSSSAP00000002671 (1)
8030.ENSSSAP00000002680 (1)
8030.ENSSSAP00000002684 (1)
8030.ENSSSAP00000002690 (1)
8030.ENSSSAP00000002813 (1)
8030.ENSSSAP00000003619 (1)
8030.ENSSSAP00000004421 (1)
8030.ENSSSAP00000004518 (1)
8030.ENSSSAP00000004639 (1)
8030.ENSSSAP00000004862 (1)
8030.ENSSSAP00000004890 (1)
8030.ENSSSAP00000005034 (1)
8030.ENSSSAP00000005299 (1)
8030.ENSSSAP00000005382 (1)
8030.ENSSSAP00000005521 (1)
8030.ENSSSAP00000005671 (1)
8030.ENSSSAP00000006110 (1)
8030.ENSSSAP00000006522 (1)
8030.ENSSSAP00000006671 (1)
8030.ENSSSAP00000006691 (1)

CHEBI ID

CHEBI:60425 (1)
CHEBI:182307 (1)
CHEBI:175196 (1)
CHEBI:132628 (1)
CHEBI:86904 (1)
CHEBI:194376 (1)
CHEBI:11814 (1)
CHEBI:67797 (1)
CHEBI:175739 (1)
CHEBI:175569 (1)
CHEBI:143762 (1)
CHEBI:185474 (1)
CHEBI:165842 (1)
CHEBI:18303 (1)
CHEBI:27847 (1)
CHEBI:192946 (1)
CHEBI:16894 (1)
CHEBI:75839 (1)
CHEBI:191711 (1)
CHEBI:5316 (1)
CHEBI:185384 (1)
CHEBI:173158 (1)
CHEBI:17980 (1)
CHEBI:168450 (1)
CHEBI:16786 (1)
CHEBI:17837 (1)
CHEBI:16337 (1)
CHEBI:17885 (1)
CHEBI:145828 (1)
CHEBI:37050 (1)

Metabolite Name

Flavone base + 3O, O-HexA (1)
5,8-Dihydroxy-3,5,8-trimethyl-4a,5,6,7,7a,8,9,9a-octahydroazuleno[6,5-b]furan-2(4H)-one (1)
Quercetin-4'-O-glucoside (1)
Uridine 5-diphosphate (1)
Propionyl coenzyme A (1)
Phosphatidic Acid (1)
Orotidine 5-monophosphate (1)
N-Formylanthranilic acid (1)
Ketoglutaric acid (1)
Inosine 5-triphosphate (1)
Guanosine 5-triphosphate (1)
Guanosine 5-diphosphate (1)
D-myo-Inositol-1,4,5-triphosphate (1)
Deoxyguanylate (1)
Cytidine 5-triphosphate (1)
Cytidine 5-diphosphocholine (1)
Cytidine 5-diphosphate (1)
Acetylamino-acetic acid (1)
6-Deoxy-L-galactonic acid (1)
3-Phosphoadenosine 5-phosphosulfate (1)
3-hydroxypentanedioic acid (1)
3-Hydroxybutyryl coenzyme A (1)
2-Deoxyuridine 5-monophosphate (1)
2-Deoxyribose-5-phosphate (1)
2-Deoxy-D-ribonic acid (1)
2-Deoxycytidine 5-diphosphate (1)
2-Deoxy-5-cytidylic acid (1)
2,3-Diphospho-D-glyceric acid (1)
2-(Hydroxymethyl)butanoic acid (1)
Uridine 5-diphosphoglucose (1)

IsPrivate

False (2)

First Public Date

2026 (3)
2025 (1)
2014 (1)

Modelling Approach

Ordinary differential equation model (2)

Study type

Transcription profiling by array (20)
RNA-seq of coding RNA (3)
Animal - One-color microarray (2)

Release Date

2021 (47)
2023 (46)
2025 (45)
2022 (43)
2024 (42)
2019 (40)
2020 (38)
2018 (23)
2016 (13)
2026 (9)
2013 (8)
2012 (8)
2008 (8)
2014 (6)
2017 (6)
2015 (6)
2011 (5)
2007 (5)
2009 (3)
2006 (3)
2005 (2)
2010 (2)
2004 (1)

Lab affiliation

Academic Unit of Reproductive and Developmental Medicine, Department of Oncology and Metabo-lism, The Medical School, University of Sheffield, Sheffield , UK And Department of Pathophysiology, Institute of Biomedicine and Translational Medicine, Faculty of Medi-cine, University of Tartu, 14B Ravila, 50411 Tartu, Estonia and Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences (1)
Aix Marseille Univ, CNRS, INSERM, Institut Paoli-Calmettes, CRCM, Marseille, France (1)
Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS) Technical University of Munich (TUM) Gregor-Mendel-Straße 4 85354 Freising GERMANY (1)
Cardiac Bioengineering group, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia (1)
Cell Signaling and Clinical Proteomics Group, Biocruces Bizkaia Health Research Institute, 48903 Barakaldo (Spain) (1)
Central Science Laboratory, University of Tasmania (1)
China University of Geosciences(Wuahn),Wuahn, China (1)
Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark (1)
Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA Stanford Genome Technology Center, Palo Alto, CA, USA Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany (1)
Department of Molecular Medicine The Scripps Research Institute (1)
Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 2Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL (1)
Division of Cardiology Johns Hopkins University School of Medicine Ross Research Building, Room 847 720 Rutland Avenue Baltimore, MD 21205 Phone: 410-614-0027 Email: dbrianfoster@jhmi.edu Web: http://web1.johnshopkins.edu/fosterlab (1)
Dow Research Institute of Biotechnology and Biomedical Sciences, Dow University of Health Sciences (1)
Dow research institute of biotechnology and biomedical sciences (1)
Helmholtz Zentrum München, Institute of Lung Biology and Disease, Member of the German Center for Lung Research (DZL), Munich, Germany (1)
Institute of Immunology and Infection Research, Ashworth Laboratories, School of Biological Sciences, University of Edinburgh, EH9 3FL, Edinburgh, United Kingdom (1)
Institute of Molecular Biology (IMB), 55128 Mainz, Germany; Institute of Developmental Biology and Neurobiology (IDN), Johannes Gutenberg University, 55128 Mainz, Germany (lab head) (1)
Max-Planck-Institute for Biology of Ageing Department of Mitochondrial Proteostasis Joseph-Stelzmann-Str. 9b 50931 Cologne (1)
Systematische Proteomforschung & Bioanalytik - Institut für Experimentelle Medizin (IEM) Christian-Albrechts-Universität zu Kiel Niemannsweg 11 (Campus UK-SH, Kiel) 24105 Kiel, Germany (1)
The Babraham Institute, Babraham Research Campus, Cambridge, UK (1)
VIB Center for Brain & Disease Research, Herestraat 49, 3000 Leuven, Belgium. (1)
Vanderbilt University (1)
iRIP Unit, Department of Biochemistry and Microbiology, Ghent University, Gent, Belgium (1)

Tags

xref:PubMed:18684314 (1)
xref:PubMed:42720472 (1)

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Development of a Method for Fast Assessment of Protein Solubility Based on Ultrasonic Dispersion and Differential Centrifugation Technology.

Not available

S-EPMC9453942 | biostudies-literature

Protein solubility and differential proteomic profiling of recombinant Escherichia coli overexpressing double-tagged fusion proteins.

Not available

S-EPMC2940792 | biostudies-literature

Polymers Enhance Chlortetracycline Hydrochloride Solubility.

Not available

S-EPMC11477051 | biostudies-literature

Gain-of-function RBM20 variants linked to severe dilated cardiomyopathy impair mitochondrial function.

We first performed solubility profiling in RBM20-WT, -P635L+/+ and -R636Q+/+ mice. We lysed murine ventricular tissues using either a mild detergent (NP-40) to extract only the soluble fraction of the proteome, or a strong detergent (SDS) to extract total proteomes, within the same experiment. Solub...

ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse)

2026-07-19 | PXD057195 | Pride